The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase (Q27630791)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11266595%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase (English)

1 reference

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Herpes simplex virus type 1

5 November 2019

main subject

1 reference

5

1 reference

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5 November 2019

author name string

C Wurth

1

1 reference

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5 November 2019

U Kessler

2

1 reference

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5 November 2019

J Vogt

3

1 reference

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5 November 2019

G E Schulz

4

1 reference

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5 November 2019

L Scapozza

6

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5 November 2019

publication date

1 January 2001

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5 November 2019

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5 November 2019

volume

10

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5 November 2019

issue

1

1 reference

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5 November 2019

page(s)

63-73

1 reference

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Nucleoside binding site of herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography

5 November 2019

cites work

1 reference

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Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine

20 March 2017

1 reference

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Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir

20 March 2017

1 reference

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Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

20 March 2017

1 reference

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Structural origins of high-affinity biotin binding to streptavidin

20 March 2017

1 reference

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Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine

20 March 2017

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20 March 2017

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20 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

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Movie of the structural changes during a catalytic cycle of nucleoside monophosphate kinases

20 March 2017

1 reference

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Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state

20 March 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

20 March 2017

1 reference

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Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase

7 April 2017

1 reference

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Enhancement of tumor ablation by a selected HSV-1 thymidine kinase mutant

29 September 2017

1 reference

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Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

29 September 2017

1 reference

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Analysis of multidimensional spectroscopic data to monitor unfolding of proteins

29 September 2017

1 reference

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Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir

29 September 2017

1 reference

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Drug sensitivity ("suicide") genes for selective cancer chemotherapy.

29 September 2017

1 reference

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Thermodynamics of the binding of L-arabinose and of D-galactose to the L-arabinose-binding protein of Escherichia coli

29 September 2017

1 reference

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Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling

29 September 2017

1 reference

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Efficient retroviral gene transfer of a Tat-regulated herpes simplex virus thymidine kinase gene for HIV gene therapy.

2 June 2018

1 reference

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The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2249856

Circular dichroism determination of class I MHC-peptide equilibrium dissociation constants

2 June 2018

1 reference

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Human epithelial ovarian cancer xenotransplants into nude mice can be cured by adenovirus-mediated thymidine kinase gene therapy

2 June 2018

1 reference

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Local regression of breast tumors following intramammary ganciclovir administration in double transgenic mice expressing neu oncogene and herpes simplex virus thymidine kinase

2 June 2018

1 reference

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In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

2 June 2018

1 reference

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Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase. A calorimetric study.

2 June 2018

1 reference

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Substrate diversity of herpes simplex virus thymidine kinase. Impact Of the kinematics of the enzyme.

27 November 2018

1 reference

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Interaction of the recombinant herpes simplex virus type 1 thymidine kinase with thymidine and aciclovir: a kinetic study

27 November 2018

1 reference

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Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: clinical follow-up and improved new vectors

27 November 2018

1 reference

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Drug resistance of herpes simplex virus type 1--structural considerations at the molecular level of the thymidine kinase.

27 November 2018

1 reference

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HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

27 November 2018

1 reference

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Gene therapy for the treatment of malignant brain tumors with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system

27 November 2018

1 reference

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The three-dimensional structure of thymidine kinase from herpes simplex virus type 1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2249856

Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+)- and (-)-enantiomers of

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11266595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11266595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1110/PS.27401

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11266595%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

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5 November 2019

PubMed publication ID

11266595

1 reference

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