Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop (Q27634754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Mark Baker

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Paul Curmi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Jankova L

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Harrop SJ

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Andrews JL

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Bertram KC

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Gould AR

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

language of work or name

English

0 references

publication date

23 August 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

11 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

43374-43382

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Evidence for intracellular cleavage of plasminogen activator inhibitor type 2 (PAI-2) in normal epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Serpin tertiary structure transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Crystal structure of uncleaved ovalbumin at 1.95 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Use of non-crystallographic symmetry in protein structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Interaction between the P14 residue and strand 2 of beta-sheet B is critical for reactive center loop insertion in plasminogen activator inhibitor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The transition between the open and closed states of rubisco is triggered by the inter-phosphate distance of the bound bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The structure of active serpin 1K from Manduca sexta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Structures of active and latent PAI-1: a possible stabilizing role for chloride ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Crystal structure of the apoptotic suppressor CrmA in its cleaved form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Structural basis of the activation and action of trypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Plasminogen Activator Inhibitor Type 2 Inhibits Tumor Necrosis Factor α-induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The ovalbumin family of serpin proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

The exon 3 encoded sequence of the intracellular serine proteinase inhibitor plasminogen activator inhibitor 2 is a protein binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Differentiating cells of murine stratified squamous epithelia constitutively express plasminogen activator inhibitor type 2 (PAI-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Isolation of a new specific plasminogen activator inhibitor from pregnancy plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Immunological Detection of Conformational Neoepitopes Associated with the Serpin Activity of Plasminogen Activator Inhibitor Type-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103021200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103021200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11546761%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference