Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1 (Q27637184)

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L B Van

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G R Andersen

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J Nyborg

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R H Buckingham

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M Kjeldgaard

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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language of work or name

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December 2001

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published in

Molecular Cell

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volume

8

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issue

6

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page(s)

1375-82

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cites work

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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

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The polypeptide chain release factor eRF1 specifically contacts the s(4)UGA stop codon located in the A site of eukaryotic ribosomes

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The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

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A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation

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Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner

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Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis.

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Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis

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Neurobiology: internal model visualized.

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The crystal structure of yeast phenylalanine tRNA at 2.0 A resolution: cleavage by Mg(2+) in 15-year old crystals

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Translational termination comes of age.

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Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

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7 January 2021

Translational termination in Escherichia coli: three bases following the stop codon crosslink to release factor 2 and affect the decoding efficiency of UGA-containing signals

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Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic

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The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis

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Functional specificity of amino acid at position 246 in the tRNA mimicry domain of bacterial release factor 2.

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The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246

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7 January 2021

Crystal structure of the ribosome at 5.5 A resolution

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