Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process (Q27639298)

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object named as

Mikel Valle

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author name string

Jayati Sengupta

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Neil K Swami

3

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Robert A Grassucci

4

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Nils Burkhardt

5

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Knud H Nierhaus

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Rajendra K Agrawal

Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation

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language of work or name

English

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publication date

1 July 2002

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published in

The EMBO Journal

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volume

21

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issue

13

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page(s)

3557-67

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cites work

1 reference

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The path of messenger RNA through the ribosome

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Recognition of cognate transfer RNA by the 30S ribosomal subunit

20 March 2017

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Crystal structure of an initiation factor bound to the 30S ribosomal subunit

20 March 2017

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Structure of the 30S ribosomal subunit

20 March 2017

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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

20 March 2017

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Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle

20 March 2017

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Solution structure of the E. coli 70S ribosome at 11.5 A resolution

20 March 2017

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X-ray crystal structures of 70S ribosome functional complexes

20 March 2017

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A detailed view of a ribosomal active site: the structure of the L11-RNA complex

20 March 2017

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Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution

20 March 2017

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An alpha to beta conformational switch in EF-Tu

20 March 2017

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Helix unwinding in the effector region of elongation factor EF-Tu-GDP

20 March 2017

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The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

20 March 2017

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Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

20 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

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The role of guanosine 5′-triphosphate in polypeptide chain elongation

20 March 2017

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Translation: in retrospect and prospect

7 April 2017

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Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms

29 September 2017

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Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures

29 September 2017

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Three-dimensional cryoelectron microscopy of ribosomes

29 September 2017

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Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome

29 September 2017

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29 September 2017

Macromolecular mimicry

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Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

29 September 2017

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Crystal structure of active elongation factor Tu reveals major domain rearrangements

29 September 2017

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The 530 loop of 16S rRNA: a signal to EF-Tu?

29 September 2017

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Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.

29 September 2017

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The structural and functional basis for the kirromycin resistance of mutant EF-Tu species in Escherichia coli

29 September 2017

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Mechanism of action of kirromycin-like antibiotics

29 September 2017

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Anticodon-anticodon interaction induces conformational changes in tRNA: yeast tRNAAsp, a model for tRNA-mRNA recognition

29 September 2017

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Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

29 September 2017

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Electron microscopy and computer image averaging of ice-embedded large ribosomal subunits from Escherichia coli

29 September 2017

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Significance of the third tRNA binding site, the E site, on E. coli ribosomes for the accuracy of translation: an occupied E site prevents the binding of non-cognate aminoacyl-tRNA to the A site

29 September 2017

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Classification of macromolecular assemblies studied as 'single particles'.

29 September 2017

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Ribotoxin recognition of ribosomal RNA and a proposal for the mechanism of translocation

29 September 2017

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Conformational changes in tRNA Consequences of aminoacylation and codon-anticodon recognition

29 September 2017

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Mechanism of the Inhibition of Protein Synthesis by Kirromycin. Role of Elongation Factor Tu and Ribosomes

29 September 2017

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Induced structural transitions in tRNA

29 September 2017

1 reference

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Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation

29 September 2017

1 reference

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Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

2 June 2018

1 reference

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EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

2 June 2018

1 reference

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Escherichia coli 70 S ribosome at 15 A resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein

2 June 2018

1 reference

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The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles

2 June 2018

1 reference

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Automatic particle picking from electron micrographs.

2 June 2018

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Self-coded 3'-extension of run-off transcripts produces aberrant products during in vitro transcription with T7 RNA polymerase

2 June 2018

1 reference

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Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126079

Intermediate states in the movement of transfer RNA in the ribosome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126079

Effects of nucleotide- and aurodox-induced changes in elongation factor Tu conformation upon its interactions with aminoacyl transfer RNA. A fluorescence study.

2 June 2018

1 reference

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Visualization of elongation factor Tu on the Escherichia coli ribosome.

2 June 2018

1 reference

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A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA.

27 November 2018

1 reference

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Mutations to kirromycin resistance occur in the interface of domains I and III of EF-Tu.GTP.

27 November 2018

1 reference

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Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

27 November 2018

1 reference

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[19] Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy

27 November 2018

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12 December 2020

Molecular Mechanics of Translation : a Reciprocating Ratchet Mechanism

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12 December 2020

The transorientation hypothesis for codon recognition during protein synthesis

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12 December 2020

The structure of yeast tRNA(Asp). A model for tRNA interacting with messenger RNA

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12 December 2020

Structure of keyhole limpet hemocyanin type 1 (KLH1) at 15 Å resolution by electron cryomicroscopy and angular reconstitution † 1 †This article is dedicated to the memory of Anneke van Heel. 1Edited by M.F. Moody

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12 December 2020

Crystal structure of yeast tRNAAsp: atomic coordinates

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12 December 2020

An A to U transversion at position 1067 of 23 S rRNA from Escherichia coli impairs EF-Tu and EF-G function 1 1Edited by D. E. Draper

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDF326

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2660123

2660123

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1 reference

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