Crystal structure of monomeric human &#160;-2-microglobulin reveals clues to its amyloidogenic properties (Q27639361)

5

object named as

Sheena E Radford

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author name string

Chi H Trinh

1

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Arnout P Kalverda

3

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Simon E V Phillips

full work available at URL

4

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language of work or name

English

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publication date

23 July 2002

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http://eprints.whiterose.ac.uk/574

content deliverer

White Rose Research Online

object has role

published version

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White Rose Research Online

Proceedings of the National Academy of Sciences of the United States of America

15 December 2018

published in

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volume

99

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page(s)

9771-6

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issue

15

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cites work

Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

20 March 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Three-dimensional structure of beta 2-microglobulin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Raster3D Version 2.0. A program for photorealistic molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

1H NMR assignments and secondary structure of human beta 2-microglobulin in solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

In vitro formation of amyloid fibrils from intact beta 2-microglobulin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Rationally designed mutations convert de novo amyloid-like fibrils into monomeric beta-sheet proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Removal of the N-terminal hexapeptide from human beta2-microglobulin facilitates protein aggregation and fibril formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Kidney dialysis-associated amyloidosis: a molecular role for copper in fiber formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

The intrachain disulfide bond of beta(2)-microglobulin is not essential for the immunoglobulin fold at neutral pH, but is essential for amyloid fibril formation at acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Structural properties of an amyloid precursor of beta(2)-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

beta 2-microglobulin can be refolded into a native state from ex vivo amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

Beta-2-microglobulin-associated amyloidosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125010

Amyloid kidney stones of uremic patients consist of beta 2-microglobulin fragments

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.152337399

21 January 2018

Identifiers

DOI

10.1073/PNAS.152337399

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2058819

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