Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions (Q27639959)

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14 December 2019

title

Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions (English)

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14 December 2019

5

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14 December 2019

3

Anthony Bretscher

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14 December 2019

author name string

William James Smith

series ordinal

1

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14 December 2019

Nicolas Nassar

series ordinal

2

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14 December 2019

Richard A Cerione

series ordinal

4

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14 December 2019

language of work or name

English

0 references

publication date

11 November 2002

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Journal of Biological Chemistry

14 December 2019

number of pages

8

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inferred from page(s)

published in

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14 December 2019

volume

278

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14 December 2019

issue

7

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14 December 2019

page(s)

4949-4956

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Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells

14 December 2019

cites work

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The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein

21 January 2018

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A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization

21 January 2018

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Radixin is a novel member of the band 4.1 family

21 January 2018

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Moesin: a member of the protein 4.1-talin-ezrin family of proteins

21 January 2018

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Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins

21 January 2018

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ERM proteins and merlin: integrators at the cell cortex

21 January 2018

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Association of ezrin with intercellular adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by phosphatidylinositol 4, 5-bisphosphate

21 January 2018

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Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

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Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

21 January 2018

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The carboxyl-terminal region of EBP50 binds to a site in the amino-terminal domain of ezrin that is masked in the dormant molecule.

21 January 2018

1 reference

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The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

21 January 2018

1 reference

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Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

21 January 2018

1 reference

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Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

21 January 2018

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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

21 January 2018

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Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

21 January 2018

1 reference

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Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210601200

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210601200

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

21 January 2018

1 reference

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Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

21 January 2018

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Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A

21 January 2018

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Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

21 January 2018

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Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

21 January 2018

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Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

21 January 2018

1 reference

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The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation

21 January 2018

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

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Validation of protein crystal structures

21 January 2018

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Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain

21 January 2018

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Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization

21 January 2018

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Dynamic information from protein crystallography. An analysis of temperature factors from refinement of the hen egg-white lysozyme structure

21 January 2018

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Refined structure of glutathione reductase at 1.54 A resolution

21 January 2018

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Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution

21 January 2018

1 reference

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Trypsinogen-trypsin transition: a molecular dynamics study of induced conformational change in the activation domain

21 January 2018

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Protein phosphorylation in response to PDGF stimulation in cultured neurons and astrocytes.

21 January 2018

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Regulation of cortical structure by the ezrin-radixin-moesin protein family

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

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Raster3D: photorealistic molecular graphics

21 January 2018

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Improved R-factors for diffraction data analysis in macromolecular crystallography

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M210601200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12429733%20AND%20SRC:MED&resulttype=core&format=json

release_p4cyppknizfptbhwpmgqg2zmsu

14 December 2019

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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