Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers (Q27639997)

9

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ORCID Public Data File 2021

author name string

Alasdair F Bell

1

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Yuguo Feng

2

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Hilary A Hofstein

3

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Sapan Parikh

4

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Jiaquan Wu

5

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Michael J Rudolph

6

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Adrian Whitty

Substrate stereochemistry of the enoyl-CoA hydratase reaction

8

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language of work or name

English

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publication date

November 2002

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published in

Chemistry and Biology

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volume

9

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issue

11

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page(s)

1247-55

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Stereospecificity of the Reaction Catalyzed by Enoyl-CoA Hydratase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Isotope effects on the crotonase reaction.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Crotonase-catalyzed beta-elimination is concerted: a double isotope effect study

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Enoyl-coenzyme A hydratase-catalyzed exchange of the alpha-protons of coenzyme A thiol esters: a model for an enolized intermediate in the enzyme-catalyzed elimination?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Enoyl-CoA Hydratase and Isomerase form a Superfamily with a Common Active-Site Glutamate Residue

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Role of glutamate 144 and glutamate 164 in the catalytic mechanism of enoyl-CoA hydratase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Mutagenic and enzymological studies of the hydratase and isomerase activities of 2-enoyl-CoA hydratase-1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Involvement of glycine 141 in substrate activation by enoyl-CoA hydratase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Electronic Rearrangement Induced by Substrate Analog Binding to the Enoyl-CoA Hydratase Active Site: Evidence for Substrate Activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Localized electron polarization in a substrate analog binding to the active site of enoyl-CoA hydratase: Raman spectroscopic and conformational analyses of rotamers of hexadienoyl thiolesters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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Molecular structures of cis- and trans-S-Ethyl thiocrotonate. A combined vibrational spectroscopic and ab initio SCF-MO study

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Structure of Hexadienoyl-CoA Bound to Enoyl-CoA Hydratase Determined by Transferred Nuclear Overhauser Effect Measurements: Mechanistic Predictions Based on the X-ray Structure of 4-(Chlorobenzoyl)-CoA Dehalogenase†

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Effect of mutagenesis on the stereochemistry of enoyl-CoA hydratase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Raman study of the polarizing forces promoting catalysis in 4-chlorobenzoate-CoA dehalogenase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Investigation of substrate activation by 4-chlorobenzoyl-coenzyme A dehalogenase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Modulating electron density in the bound product, 4-hydroxybenzoyl-CoA, by mutations in 4-chlorobenzoyl-CoA dehalogenase near the 4-hydroxy group

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Studies on the inactivation of bovine liver enoyl-CoA hydratase by (methylenecyclopropyl)formyl-CoA: elucidation of the inactivation mechanism and identification of cysteine-114 as the entrapped nucleophile

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Mechanism for the recognition and activation of substrate in medium-chain acyl-CoA dehydrogenase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Polarization of cinnamoyl-CoA substrates bound to enoyl-CoA hydratase: correlation of (13)C NMR with quantum mechanical calculations and calculation of electronic strain energy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Direct observation of substrate distortion by triosephosphate isomerase using Fourier transform infrared spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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Polarization of substrate carbonyl groups by yeast aldolase: investigation by Fourier transform infrared spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Resonance Raman study on complexes of medium-chain acyl-CoA dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

The importance of binding energy in catalysis of hydride transfer by UDP-galactose 4-epimerase: a 13C and 15N NMR and kinetic study

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Stereoelectronic activation of methylenetetrahydrofolate by thymidylate synthase: resonance Raman spectroscopic evidence

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Ultraviolet resonance Raman spectroscopy of delta 5-3-ketosteroid isomerase revisited: substrate polarization by active-site residues

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Raman spectroscopic studies of the structures, energetics, and bond distortions of substrates bound to enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Multiple conformations of the acylenzyme formed in the hydrolysis of methicillin by Citrobacter freundii beta-lactamase: a time-resolved FTIR spectroscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Molecular Architecture and Biological Reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Chemical basis for enzyme catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

The depth of chemical time and the power of enzymes as catalysts.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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Remarkable rate enhancement of orotidine 5'-monophosphate decarboxylase is due to transition-state stabilization rather than to ground-state destabilization.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

7 January 2021

Environmental effects on phosphoryl group bonding probed by vibrational spectroscopy: implications for understanding phosphoryl transfer and enzymatic catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900263-6

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