NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH (Q27640008)

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15 December 2019

title

NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH (English)

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15 December 2019

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Lacticaseibacillus casei

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1

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15 December 2019

author name string

Eugeni G Smirnov

2

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15 December 2019

Berry Birdsall

3

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15 December 2019

James Feeney

5

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15 December 2019

Geoff Kelly

4

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15 December 2019

publication date

1 September 2002

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Journal of Biomolecular NMR

15 December 2019

published in

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15 December 2019

volume

24

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15 December 2019

issue

1

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15 December 2019

page(s)

67-70

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Characterization of rates of ring-flipping in trimethoprim in its ternary complexes with Lactobacillus casei dihydrofolate reductase and coenzyme analogues

15 December 2019

cites work

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12 December 2020

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

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12 December 2020

Inhibition of dihydrofolate reductase: effect of reduced nicotinamide adenine dinucleotide phosphate on the selectivity and affinity of diaminobenzylpyrimidines

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Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

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The charge state of trimethoprim bound to Lactobacillus casei dihydrofolate reductase

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12 December 2020

Trimethoprim binds in a bacterial mode to the wild-type and E30D mutant of mouse dihydrofolate reductase.

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Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.

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Basis of selectivity of antibacterial diaminopyrimidines.

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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12 December 2020

Solution structure of bound trimethoprim in its complex with Lactobacillus casei dihydrofolate reductase.

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12 December 2020

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

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12 December 2020

Multinuclear NMR characterization of two coexisting conformational states of the Lactobacillus casei dihydrofolate reductase-trimethoprim-NADP complex

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12 December 2020

Effects of coenzyme analogues on the binding of p-aminobenzoyl-L-glutamate and 2,4-diaminopyrimidine to Lactobacillus casei dihydrofolate reductase.

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12 December 2020

Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system.

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12 December 2020

The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate

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12 December 2020

NMR detection of arginine-ligand interactions in complexes of Lactobacillus casei dihydrofolate reductase

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12 December 2020

Structure and dynamics in solution of the complex of lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate

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12 December 2020

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim

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12 December 2020

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

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12 December 2020

The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution

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12 December 2020

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate

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12 December 2020