On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase (Q27640074)

7

0 references

Michael Weyand

2

0 references

Demet Araç

5

object named as

Demet Arac

0 references

Ralf Seidel

3

object named as

Ralf Seidel

0 references

author name string

Victor Kulik

1

0 references

Dimitri Niks

4

0 references

Michael F Dunn

Journal of Molecular Biology

6

0 references

language of work or name

English

0 references

publication date

6 December 2002

0 references

published in

0 references

volume

324

0 references

issue

4

0 references

page(s)

677-90

0 references

cites work

The molecular basis of substrate channeling

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Allosteric linkages between beta-site covalent transformations and alpha-site activation and deactivation in the tryptophan synthase bienzyme complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha 2 beta 2 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Monovalent metal ions play an essential role in catalysis and intersubunit communication in the tryptophan synthase bienzyme complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Mechanisms of monovalent cation action in enzyme catalysis: the tryptophan synthase alpha-, beta-, and alpha beta-reactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Loop closure and intersubunit communication in tryptophan synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Subunit communication in the tryptophan synthase alpha 2 beta 2 complex. Effects of beta subunit ligands on proteolytic cleavage of a flexible loop in the alpha subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Crystal structure of wild-type tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

THE COMPLETE AMINO ACID SEQUENCE OF THE TRYPTOPHAN SYNTHETASE A PROTEIN (alpha SUBUNIT) AND ITS COLINEAR RELATIONSHIP WITH THE GENETIC MAP OF THE A GENE

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Detection and identification of intermediates in the reaction of L-serine with Escherichia coli tryptophan synthase via rapid-scanning ultraviolet-visible spectroscopy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Mechanisms of monovalent cation action in enzyme catalysis: the first stage of the tryptophan synthase beta-reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Stereoelectronic control of bond formation in Escherichia coli tryptophan synthase: substrate specificity and enzymatic synthesis of the novel amino acid dihydroisotryptophan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Allosteric communication of tryptophan synthase. Functional and regulatory properties of the beta S178P mutant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Steady-state kinetic studies of the synthesis of indoleglycerol phosphate catalyzed by the alpha subunit of tryptophan synthase from Escherichia coli. Comparison with the alpha2 beta2-complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Tryptophan synthase from Escherichia coli and Salmonella typhimurium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Improved methods for building protein models in electron density maps and the location of errors in these models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Comparison, assessment and classification of protein 3D structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

Raster3D Version 2.0. A program for photorealistic molecular graphics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901109-9