The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors (Q27640631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Robert N Jorissen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Thomas P J Garrett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Neil M McKern

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Meizhen Lou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Thomas C Elleman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

George O Lovrecz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Michael Kofler

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Edouard C Nice

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Antony W Burgess

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Colin W Ward

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

publication date

1 February 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

495-505

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Disabling erbB receptors with rationally designed exocyclic mimetics of antibodies: structure-function analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Disabling receptor ensembles with rationally designed interface peptidomimetics

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

HER2/neu: mechanisms of dimerization/oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Structure of the extracellular region of HER3 reveals an interdomain tether

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

The ErbB receptor family: a therapeutic target for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Extracellular domains drive homo- but not hetero-dimerization of erbB receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Binding specificities and affinities of egf domains for ErbB receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

The role of distinct p185neu extracellular subdomains for dimerization with the epidermal growth factor (EGF) receptor and EGF-mediated signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Shape complementarity at protein/protein interfaces

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

The EGF receptor family as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

A linear region of a monoclonal antibody conformational epitope mapped on p185HER2 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Domain-specific Interactions between the p185neuand Epidermal Growth Factor Receptor Kinases Determine Differential Signaling Outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Mutagenesis reveals a role for epidermal growth factor receptor extracellular subdomain IV in ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Val(659)-->Glu mutation within the transmembrane domain of ErbB-2: effects measured by (2)H NMR in fluid phospholipid bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Effect of ErbB2 coexpression on the kinetic interactions of epidermal growth factor with its receptor in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Untangling the ErbB signalling network

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Anti-ErbB-2 monoclonal antibodies and ErbB-2-directed vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

Identification of epitope regions recognized by tumor inhibitory and stimulatory anti-ErbB-2 monoclonal antibodies: implications for vaccine design

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900048-0

7 January 2021

10.1016/S1097-2765(03)00048-0

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

4043988

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620236%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

4043988

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4043988