Structural basis for the antibiotic activity of ketolides and azalides (Q27640646)

6

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Heike Bartels

5

object named as

Heike Bartels

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Frank Schluenzen

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ORCID Public Data File 2021

author name string

Frank Schlünzen

1

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Jörg M Harms

2

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Francois Franceschi

3

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Harly A S Hansen

A detailed view of a ribosomal active site: the structure of the L11-RNA complex

4

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publication date

March 2003

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published in

Structure

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volume

11

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issue

3

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page(s)

329-38

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cites work

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

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The structures of four macrolide antibiotics bound to the large ribosomal subunit

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Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides

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Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens

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Interactions of Macrolide Antibiotics (Erythromycin A, Roxithromycin, Erythromycylamine [Dirithromycin], and Azithromycin) with Phospholipids: Computer-Aided Conformational Analysis and Studies on Acellular and Cell Culture Models

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Multidrug-resistant bacteria: overcoming antibiotic permeability barriers of gram-negative bacteria

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Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria

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Intracellular activity of azithromycin against bacterial enteric pathogens

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In vitro activity of azithromycin against bacterial enteric pathogens

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The macrolides: erythromycin, clarithromycin, and azithromycin

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Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains

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In-vitro activities of 14-, 15- and 16-membered macrolides against gram-positive cocci

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Ketolides lack inducibility properties of MLS(B) resistance phenotype

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Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA

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Antipneumococcal activity of ABT-773 compared to those of 10 other agents

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A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin

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Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumon

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A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre

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The in vitro activity of ABT773, a new ketolide antimicrobial agent

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Susceptibilities of Haemophilus influenzae and Moraxella catarrhalis to ABT-773 compared to their susceptibilities to 11 other agents

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The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA.

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Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA

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Insights into the mechanism of azithromycin interaction with an Escherichia coli functional ribosomal complex

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L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin

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Biochemical and genetic studies on two different types of erythromycin resistant mutants of Escherichia coli with altered ribosomal proteins

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The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22.

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Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells

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A Comparison of the Inhibition of Translation and 50S Ribosomal Subunit Formation in Staphylococcus aureus Cells by Nine Different Macrolide Antibiotics

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High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

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Processing of X-ray diffraction data collected in oscillation mode

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