X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease (Q27641402)

7

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Anthony H. Futerman

object named as

Anthony H Futerman

6

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author name string

Hay Dvir

1

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Michal Harel

2

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Andrew A McCarthy

3

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Lilly Toker

Crystal structure of saposin B reveals a dimeric shell for lipid binding

4

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publication date

July 2003

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published in

EMBO Reports

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volume

4

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issue

7

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page(s)

704-9

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cites work

1 reference

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20 March 2017

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Crystal structure of the beta-glycosidase from the hyperthermophile Thermosphaera aggregans: insights into its activity and thermostability

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Updating the sequence-based classification of glycosyl hydrolases

20 March 2017

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New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

20 March 2017

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Human acid beta-glucosidase: isolation and amino acid sequence of a peptide containing the catalytic site

20 March 2017

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Methods used in the structure determination of bovine mitochondrial F1 ATPase

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20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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20 March 2017

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20 March 2017

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The active site of human glucocerebrosidase: structural predictions and experimental validations

20 March 2017

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20 March 2017

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Structures and mechanisms of glycosyl hydrolases

20 March 2017

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Prediction of protein antigenic determinants from amino acid sequences

20 March 2017

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Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

7 April 2017

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Human glucocerebrosidase: heterologous expression of active site mutants in murine null cells

29 September 2017

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The Gaucher registry: demographics and disease characteristics of 1698 patients with Gaucher disease

29 September 2017

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Prevalence of lysosomal storage disorders

29 September 2017

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Acid beta-glucosidase: enzymology and molecular biology of Gaucher disease

29 September 2017

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Protein structural topology: Automated analysis and diagrammatic representation.

29 September 2017

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Lysosomal degradation on vesicular membrane surfaces. Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators.

2 June 2018

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Human acid beta-glucosidase. N-glycosylation site occupancy and the effect of glycosylation on enzymatic activity.

2 June 2018

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Analysis of human acid beta-glucosidase by site-directed mutagenesis and heterologous expression.

2 June 2018

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Analysis of glucocerebrosidase activity using N-(1-[14C]hexanoyl)-D-erythroglucosylsphingosine demonstrates a correlation between levels of residual enzyme activity and the type of Gaucher disease

2 June 2018

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2 June 2018

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Crystallization and preliminary X-ray analysis of recombinant human acid beta-glucocerebrosidase, a treatment for Gaucher's disease

2 June 2018

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Effect of mutations within the peripheral anionic site on the stability of acetylcholinesterase

27 November 2018

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The effect of hydrogen bonds on the conformation of glycosphingolipids. Methylated and unmethylated cerebroside studied by X-ray single crystal analysis and model calculations

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

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12 December 2020

Identification of Glu340 as the active-site nucleophile in human glucocerebrosidase by use of electrospray tandem mass spectrometry

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12 December 2020

Enzyme therapy in type 1 Gaucher disease: comparative efficacy of mannose-terminated glucocerebrosidase from natural and recombinant sources

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12 December 2020

Site actif de la glucocérébrosidase humaine : prédictions structurales et validations expérimentales

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.EMBOR873

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOR.EMBOR873

1 reference

1 reference

1 reference

PubMed publication ID

12792654

1 reference