Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides (Q27642117)

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David Baltimore

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object named as

D Baltimore

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author name string

G Waksman

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D Kominos

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S C Robertson

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N Pant

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R B Birge

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H Hanafusa

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B J Mayer

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M D Resh

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C B Rios

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L Silverman

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J Kuriyan

Oncogenes and signal transduction

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language of work or name

English

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publication date

20 August 1992

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published in

Nature

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volume

358

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issue

6388

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page(s)

646-53

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cites work

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Protein kinase activity associated with the avian sarcoma virus src gene product

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Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein

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Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

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Signal transduction by receptors with tyrosine kinase activity

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A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

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Cloning of bovine GAP and its interaction with oncogenic ras p21.

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A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

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A novel viral oncogene with structural similarity to phospholipase C

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Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

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Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

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Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

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7 January 2021

Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src

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7 January 2021

Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain

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7 January 2021

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

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7 January 2021

Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src

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Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants

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Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells

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7 January 2021

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor

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7 January 2021

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

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7 January 2021

Amino-aromatic interactions in proteins

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Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II

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Assignment of asparagine-44 side-chain primary amide 1H NMR resonances and the peptide amide N1H resonance of glycine-37 in basic pancreatic trypsin inhibitor

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Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

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Aromatic rings act as hydrogen bond acceptors

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Conservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domains

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

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INTERMOLECULAR CROSS LINKING OF A PROTEIN IN THE CRYSTALLINE STATE: CARBOXYPEPTIDASE-A

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Structure of iron superoxide dismutase from Pseudomonas ovalis at 2.9-A resolution

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Unbiased three-dimensional refinement of heavy-atom parameters by correlation of origin-removed Patterson functions

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Atomic structure of the actin:DNase I complex

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Primary sequence and developmental expression of a novel Drosophila melanogaster src gene

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7 January 2021

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

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7 January 2021

Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

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7 January 2021

Corrections to the nucleotide sequence of the src gene of Rous sarcoma virus

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7 January 2021

Use of T7 RNA polymerase to direct expression of cloned genes

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7 January 2021

Refinement of the influenza virus hemagglutinin by simulated annealing

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7 January 2021

The interpretation of protein structures: Estimation of static accessibility

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7 January 2021