The Influence of Hinge Region Residue Glu-381 on Antithrombin Allostery and Metastability (Q27642566)

https://api.crossref.org/works/10.1074/JBC.M311644200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

3 April 2024

author name string

Daniel J. D. Johnson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623882

3 April 2024

James A. Huntington

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623882

3 April 2024

language of work or name

English

0 references

publication date

6 February 2004

0 references

17 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623882

full work available at URL

3 April 2024

http://www.jbc.org/content/279/6/4913.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623882

https://api.elsevier.com/content/article/PII:S0021925820750817?httpAccept=text/xml

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

https://api.elsevier.com/content/article/PII:S0021925820750817?httpAccept=text/plain

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

https://syndication.highwire.org/content/doi/10.1074/jbc.M311644200

3 April 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

Journal of Biological Chemistry

3 April 2024

published in

0 references

volume

279

0 references

issue

6

0 references

page(s)

4913-21

0 references

cites work

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Mechanisms of glycosaminoglycan activation of the serpins in hemostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Crystal structure of antithrombin in a heparin-bound intermediate state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The intact and cleaved human antithrombin III complex as a model for serpin–proteinase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Biological implications of a 3 A structure of dimeric antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The anticoagulant activation of antithrombin by heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Heparin-induced substrate behavior of antithrombin Cambridge II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Antithrombin-heparin affinity reduced by fucosylation of carbohydrate at asparagine 155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The oligosaccharide side chain on Asn-135 of alpha-antithrombin, absent in beta-antithrombin, decreases the heparin affinity of the inhibitor by affecting the heparin-induced conformational change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The effect of a reducing-end extension on pentasaccharide binding by antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Lysine 114 of antithrombin is of crucial importance for the affinity and kinetics of heparin pentasaccharide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Heparin-dependent modification of the reactive center arginine of antithrombin and consequent increase in heparin binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

The role of Arg46 and Arg47 of antithrombin in heparin binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Helix D elongation and allosteric activation of antithrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Introduction of a mutation in the shutter region of antithrombin (Phe77 --> Leu) increases affinity for heparin and decreases thermal stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

RNA double-helical fragments at atomic resolution. II. The crystal structure of sodium guanylyl-3',5'-cytidine nonahydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Role of arginine 129 in heparin binding and activation of antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311644200

Ion effects on ligand-nucleic acid interactions

21 January 2018

series ordinal

25

1 reference

https://api.crossref.org/works/10.1074/JBC.M311644200

3 April 2024

Identifiers

0 references