Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates (Q27643062)

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English	Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates	scientific article

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17 November 2019

Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates (English)

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Europe PubMed Central

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17 November 2019

protein structure

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solution structure

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17 November 2019

Philippe Barthe

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17 November 2019

Marc-Henri Stern

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17 November 2019

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Marie-Thérèse Augé-Sénégas

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17 November 2019

Masayuki Noguchi

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17 November 2019

Christian Roumestand

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17 November 2019

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1 February 2004

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17 November 2019

Journal of Biomolecular NMR

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17 November 2019

28

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17 November 2019

2

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17 November 2019

137-155

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17 November 2019

Internal mobility in the partially folded DNA binding and dimerization domains of GAL4: NMR analysis of the N-H spectral density functions

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Pleckstrin domain homology

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https://pubmed.ncbi.nlm.nih.gov/14755158

12 December 2020

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Mechanism of activation of protein kinase B by insulin and IGF-1

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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1 reference

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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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https://pubmed.ncbi.nlm.nih.gov/14755158

12 December 2020

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Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy

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12 December 2020

based on heuristic

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Spectral density function mapping using 15N relaxation data exclusively

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12 December 2020

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Reassessment of Ellman's reagent

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Assignment of NH resonances in nucleic acids using natural abundance 15 N-1 H correlation spectroscopy with spin-echo and gradient pulses

1 reference

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Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data

1 reference

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The protooncogene TCL1 is an Akt kinase coactivator

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Abnormalities at 14q32.1 in T cell malignancies involve two oncogenes

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Microdrop screening: a rapid method to optimize solvent conditions for NMR spectroscopy of proteins

1 reference

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Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1

1 reference

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

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The PH domain: a common piece in the structural patchwork of signalling proteins

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Protein dynamics studied by rotating frame 15N spin relaxation times.

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Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

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A novel approach for sequential assignment of 1H, 13C, and 15N spectra of proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

1 reference

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MOLMOL: a program for display and analysis of macromolecular structures

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Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase

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A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane

1 reference

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12 December 2020

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Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

1 reference

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Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

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12 December 2020

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PH domain: the first anniversary

1 reference

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12 December 2020

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Expression of p13MTCP1 is restricted to mature T-cell proliferations with t(X;14) translocations

1 reference

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12 December 2020

based on heuristic

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Pleckstrin homology domains.

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https://pubmed.ncbi.nlm.nih.gov/14755158

12 December 2020

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Cellular survival: a play in three Akts

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Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology

1 reference

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12 December 2020

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Protein backbone dynamics revealed by quasi spectral density function analysis of amide N-15 nuclei

1 reference

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12 December 2020

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The 8 kD product of the putative oncogene MTCP-1 is a mitochondrial protein

1 reference

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12 December 2020

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

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1 reference

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1 reference

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1 reference

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A comprehensive analysis of multifield 15N relaxation parameters in proteins: determination of 15N chemical shift anisotropies.

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1 reference

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Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains

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1 reference

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1 reference

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1 reference

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