Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation (Q27643673)

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Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation
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    Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation (English)
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    Shaun R Stauffer
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    Matthew G Stanton
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    Alison R Gregro
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    Melissa A Steinbeiser
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    Jennifer R Shaffer
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    Philippe G Nantermet
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    Kenneth E Rittle
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    Dennis Collusi
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    Amy S Espeseth
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    Ming-Tain Lai
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    Beth L Pietrak
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    M Katharine Holloway
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    Georgia B McGaughey
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    Sanjeev K Munshi
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    Jerome H Hochman
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    Adam J Simon
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    Harold G Selnick
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    Samuel L Graham
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    Joseph P Vacca
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    15 March 2007
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    17
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    6
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    1788-92
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