Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 (Q27644478)

alpha-D-mannosyl-(1->3)-[alpha-D-mannosyl-(1->3)-[alpha-D-mannosyl-(1->6)]-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine

ChEBI release 2020-05-28

ChEBI ID

87337

1 reference

alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-alpha-D-Manp-(1->6)]-beta-D-Manp

ChEBI release 2020-05-28

ChEBI ID

71514

1 reference

ChEBI release 2020-05-28

1 reference

5

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Ivelin S. Georgiev

21

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Stephanie Moquin

25

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Chris Carrico

Chris Carrico

3

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Jason Gorman

Jason Gorman

4

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Tongqing Zhou

Tongqing Zhou

16

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Saidi H Kapiga

Saidi H Kapiga

30

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Ian Andrew Wilson

46

Ian A Wilson

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John R. Mascola

42

John R Mascola

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Lai-Xi Wang

Lai-Xi Wang

39

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Barton Haynes

32

Barton F Haynes

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Gary Nabel

43

Gary J Nabel

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Zhi-Yong Yang

27

Zhi-Yong Yang

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William R Schief

44

William R Schief

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Peter D. Kwong

47

Peter D Kwong

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Mallika Sastry

9

Mallika Sastry

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Dennis R. Burton

33

Dennis R Burton

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Jason S. McLellan

1

Jason S McLellan

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Andrew B Ward

45

Andrew B Ward

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James Arthos

40

James Arthos

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Richard T. Wyatt

37

Richard Wyatt

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Jeffrey C Boyington

18

Jeffrey C Boyington

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Kaifan Dai

10

Kaifan Dai

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Mark K. Louder

24

Mark K Louder

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Marie Pancera

2

Marie Pancera

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Sijy O'Dell

11

Sijy O'Dell

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Yongping Yang

14

Yongping Yang

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Mattia Bonsignori

28

Mattia Bonsignori

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John Crump

29

John A Crump

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Wayne C Koff

34

Wayne C Koff

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Syed Shahzad-Ul-Hussan

13

Syed Shahzad-ul-Hussan

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Stephen D Schmidt

26

Stephen D Schmidt

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Laura M Walker

35

Laura M Walker

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Carole A. Bewley

41

Carole A Bewley

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Sanjay Phogat

36

Sanjay Phogat

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Robert K Louder

7

Robert Louder

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Jared Orwenyo

38

Jared Orwenyo

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Baoshan Zhang

15

Baoshan Zhang

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Young Do Kwon

22

Young Do Kwon

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author name string

Reza Khayat

6

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Robert Pejchal

8

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Nikita Patel

12

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Jiang Zhu

17

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Gwo-Yu Chuang

19

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Devan Diwanji

20

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Doyung Lee

23

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Noel E Sam

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

31

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language of work or name

English

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publication date

23 November 2011

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published in

Nature

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volume

480

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page(s)

336-43

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issue

7377

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cites work

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Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

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20 March 2017

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

20 March 2017

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

20 March 2017

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Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D

20 March 2017

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20 March 2017

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20 March 2017

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Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

20 March 2017

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

20 March 2017

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

20 March 2017

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29 September 2017

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A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

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Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positio

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The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection

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29 September 2017

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Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans

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Identifiers

DOI

10.1038/NATURE10696

1 reference

Dimensions Publication ID

415010

1016437859

0 references

415010

1 reference

1 reference

1 reference