Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK (Q27644837)

Rap guanine nucleotide exchange factor 1

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SOS Ras/Rac guanine nucleotide exchange factor 1

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Dedicator of cytokinesis 1

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ABL proto-oncogene 1, non-receptor tyrosine kinase

1 reference

9

Fuyuhiko Inagaki

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author name string

Yoshihiro Kobashigawa

1

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Mieko Sakai

2

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Masato Naito

3

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Masashi Yokochi

4

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Hiroyuki Kumeta

5

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Yoshinori Makino

6

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Kenji Ogura

7

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Shinya Tanaka

Nature Structural & Molecular Biology

8

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language of work or name

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June 2007

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published in

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volume

14

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issue

6

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page(s)

503-10

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cites work

Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells

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Two species of human CRK cDNA encode proteins with distinct biological activities

21 January 2018

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Activation of c-Src in cells bearing v-Crk and its suppression by Csk

21 January 2018

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Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

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Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

31 March 2020

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

31 March 2020

1 reference

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

31 March 2020

1 reference

Crk family adaptors-signalling complex formation and biological roles

31 March 2020

1 reference

Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS.

31 March 2020

1 reference

Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancers

31 March 2020

1 reference

Gene-expression profiles predict survival of patients with lung adenocarcinoma

31 March 2020

1 reference

Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas

31 March 2020

1 reference

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at distal 17p13.3 in human lung cancer.

31 March 2020

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Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines

31 March 2020

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c-Abl kinase regulates the protein binding activity of c-Crk

31 March 2020

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Direct demonstration of an intramolecular SH2-phosphotyrosine interaction in the Crk protein

31 March 2020

1 reference

A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo.

31 March 2020

1 reference

Generation of a dual-labeled fluorescence biosensor for Crk-II phosphorylation using solid-phase expressed protein ligation

31 March 2020

1 reference

Solution structure of Grb2 reveals extensive flexibility necessary for target recognition

31 March 2020

1 reference

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide

31 March 2020

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

31 March 2020

1 reference

A potential SH3 domain-binding site in the Crk SH2 domain

31 March 2020

1 reference

Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

31 March 2020

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Crk family adaptor proteins trans-activate c-Abl kinase

31 March 2020

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C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF

31 March 2020

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Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

31 March 2020

1 reference

Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II.

31 March 2020

1 reference

Proline cis-trans isomerization controls autoinhibition of a signaling protein

31 March 2020

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The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

31 March 2020

1 reference

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

31 March 2020

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Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form

31 March 2020

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Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB1241

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3251667

1006835088

0 references

Fatcat ID

release_uqzbcqdr6ndjpfqphm3rr7e6aa

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uqzbcqdr6ndjpfqphm3rr7e6aa

mapped directly with Wikidata item

24 November 2022

based on heuristic

3251667

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference