Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha (Q27645411)

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English	Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha	scientific article

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scholarly article

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Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha (English)

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Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Yi Zhou

1

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Ute Müh

2

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Brian L Hanzelka

3

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Doug J Bartels

4

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Yunyi Wei

5

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B Govinda Rao

6

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Debra L Brennan

7

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Ann M Tigges

8

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Lora Swenson

9

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Ann D Kwong

10

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Chao Lin

11

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language of work or name

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publication date

3 August 2007

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Journal of Biological Chemistry

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282

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31

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22619-28

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

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1 reference

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1 reference

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

1 reference

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

1 reference

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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

1 reference

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A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates

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Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping

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Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization

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Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes

1 reference

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VX-950, a Novel Hepatitis C Virus (HCV) NS3-4A Protease Inhibitor, Exhibits Potent Antiviral Activities in HCV Replicon Cells

1 reference

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1 reference

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21 January 2018

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10.1074/JBC.M610207200

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