The tertiary structure and domain organization of coagulation factor VIII (Q27648918)

2

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Chong-Hwan Chang

3

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Jae-Wook Huh

4

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Jung-Sik Lee

5

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Jeanman Kim

6

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Young-Ho Kim

7

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Barry L Stoddard

Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites

8

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language of work or name

English

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publication date

1 February 2008

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published in

Blood

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volume

111

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issue

3

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page(s)

1240-7

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cites work

1 reference

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Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII

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The Protein Data Bank

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Structure of the C2 domain of human factor VIII at 1.5 A resolution

20 March 2017

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Crystal structures of the membrane-binding C2 domain of human coagulation factor V

20 March 2017

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20 March 2017

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The finer things in X-ray diffraction data collection

20 March 2017

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Rapid automated molecular replacement by evolutionary search

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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The discoidin domain family revisited: new members from prokaryotes and a homology-based fold prediction

20 March 2017

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Molecular cloning of a cDNA encoding human antihaemophilic factor

20 March 2017

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Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

20 March 2017

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Structure of human factor VIII

20 March 2017

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Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

20 March 2017

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The coagulation cascade: initiation, maintenance, and regulation

20 March 2017

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Strategies towards a longer acting factor VIII.

20 March 2017

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29 September 2017

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The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function

29 September 2017

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WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.

29 September 2017

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AN ENZYME CASCADE IN THE BLOOD CLOTTING MECHANISM, AND ITS FUNCTION AS A BIOCHEMICAL AMPLIFIER.

29 September 2017

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Optimization of factor VIII replacement therapy: can structural studies help in evading antibody inhibitors?

29 September 2017

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Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

29 September 2017

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New insights into binding interfaces of coagulation factors V and VIII and their homologues lessons from high resolution crystal structures

29 September 2017

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Biochemistry and physiology of blood coagulation.

29 September 2017

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The life cycle of coagulation factor VIII in view of its structure and function

29 September 2017

1 reference

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Identification and functional requirement of Cu(I) and its ligands within coagulation factor VIII.

29 September 2017

1 reference

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Hemophilia treatment in historical perspective: a review of medical and social developments

29 September 2017

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Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation

29 September 2017

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pH-dependent association of factor VIII chains: enhancement of affinity at physiological pH by Cu2+.

29 September 2017

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Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

2 June 2018

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Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis

2 June 2018

1 reference

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Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities

2 June 2018

1 reference

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The preparation and phospholipid binding property of the C2 domain of human factor VIII

27 November 2018

1 reference

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3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography

27 November 2018

1 reference

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Purification of recombinant human B-domain-deleted factor VIII using anti-factor VIII monoclonal antibody selected by the surface plasmon resonance biosensor.

27 November 2018

1 reference

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Comparison of the properties of phospholipid surfaces formed on HPA and L1 biosensor chips for the binding of the coagulation factor VIII.

27 November 2018

1 reference

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Hemophilic factor VIII C1- and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure

27 November 2018

1 reference

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A molecular model for the triplicated A domains of human factor VIII based on the crystal structure of human ceruloplasmin.

27 November 2018

1 reference

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Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.

27 November 2018

1 reference

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Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene, second edition

27 November 2018

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12 December 2020

Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII

1 reference

12 December 2020

Biochemical and molecular aspects of the coagulation cascade

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12 December 2020

The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor

1 reference

12 December 2020

Homology models of the C domains of blood coagulation factors V and VIII: a proposed membrane binding mode for FV and FVIII C2 domains

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12 December 2020

Role of factor VIII C2 domain in factor VIII binding to factor Xa

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12 December 2020

The Role of Platelets in Intrinsic Factor-Xa Formation

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12 December 2020

The role of phospholipid and factor VIIIa in the activation of bovine factor X

1 reference

12 December 2020

Coagulation Factor V contains copper ion

1 reference

12 December 2020

A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor

1 reference

12 December 2020

Characterization of the interaction between the A2 subunit and A1/A3-C1-C2 dimer in human factor VIIIa

1 reference

12 December 2020

1 reference

12 December 2020

A role for the C2 domain of factor VIII in binding to von Willebrand factor

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12 December 2020