Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase (Q27649781)

19 October 2023

14

Alberto Podjarny

Alberto

Podjarny

1 reference

19 October 2023

Alexandra Cousido-Siah

10

object named as

Alexandra Cousido-Siah

Alexandra

Cousido-Siah

1 reference

19 October 2023

Flora Meilleur

5

Flora

Meilleur

1 reference

19 October 2023

Matthew P Blakeley

1

Matthew P

Blakeley

1 reference

19 October 2023

Dean Myles

13

Dean

Myles

1 reference

19 October 2023

Oscar N Ventura

9

Oscar N

Ventura

1 reference

19 October 2023

8

Pavel Afonine

Pavel

Afonine

1 reference

19 October 2023

Federico Ruiz

2

Federico

Ruiz

1 reference

19 October 2023

Raul Cachau

3

Raul

Cachau

1 reference

19 October 2023

Isabelle Hazemann

4

Isabelle

Hazemann

1 reference

19 October 2023

Andre Mitschler

6

Andre

Mitschler

1 reference

19 October 2023

Stephan Ginell

7

Stephan

Ginell

1 reference

19 October 2023

Michael Haertlein

11

Michael

Haertlein

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

0 references

publication date

12 February 2008

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published in

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volume

105

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issue

6

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page(s)

1844-8

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cites work

Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

SHELXL: high-resolution refinement

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

PHENIX: building new software for automated crystallographic structure determination

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

20 March 2017

https://api.crossref.org/works/10.1073%2FPNAS.0711659105

Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

Hydrogen and hydration in proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

A neutron image plate quasi-Laue diffractometer for protein crystallography.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538850

A Theory of Water and Ionic Solution, with Particular Reference to Hydrogen and Hydroxyl Ions

29 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711659105

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711659105

Multiple proton translocation in biomolecular systems: concerted to stepwise transition in a simple model

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711659105

Modelling the catalytic reaction in human aldose reductase

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18250329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18250329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular modeling studies of the binding modes of aldose reductase inhibitors at the active site of human aldose reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18250329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0711659105

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0 references

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