Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage (Q27649833)

20 October 2023

John K Lee

2

John K

Lee

1 reference

20 October 2023

Richard Tjhen

3

Richard

Tjhen

1 reference

20 October 2023

Robert M Stroud

4

Robert M

Stroud

1 reference

20 October 2023

Thomas L James

5

Thomas L

James

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 October 2023

language of work or name

English

0 references

publication date

19 February 2008

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published in

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volume

105

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issue

7

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page(s)

2391-6

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cites work

Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

20 March 2017

1 reference

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

20 March 2017

1 reference

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Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography

20 March 2017

1 reference

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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

20 March 2017

1 reference

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Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Likelihood-enhanced fast translation functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

20 March 2017

1 reference

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Role for a bidentate ribonuclease in the initiation step of RNA interference

20 March 2017

1 reference

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RNA interference is mediated by 21- and 22-nucleotide RNAs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Automated MAD and MIR structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

20 March 2017

1 reference

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20 March 2017

1 reference

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Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

20 March 2017

1 reference

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20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Structural basis for double-stranded RNA processing by Dicer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Inhibition of translational initiation by Let-7 MicroRNA in human cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

20 March 2017

RNA silencing in plants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Bovine pancreatic ribonuclease A as a model of an enzyme with multiple substrate binding sites

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Single processing center models for human Dicer and bacterial RNase III

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Structural biology of RNA silencing and its functional implications

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Molecular mechanism of target RNA transcript recognition by Argonaute-guide complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Experimental and computational investigations of Ser10 and Lys13 in the binding and cleavage of DNA substrates by Escherichia coli DNA topoisomerase I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

RNase III enzymes and the initiation of gene silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Intermediate states of ribonuclease III in complex with double-stranded RNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Noncatalytic assembly of ribonuclease III with double-stranded RNA.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711506105

Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711506105

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711506105

The mechanism of binding of a polynucleotide chain to pancreatic ribonuclease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268147

Free energy calculations by computer simulation

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0711506105

1 reference

ADS bibcode

2008PNAS..105.2391D

0 references

1 reference

1 reference

1 reference