SNAP-25 Substrate Peptide (Residues 180-183) Binds to but Bypasses Cleavage by Catalytically Active Clostridium botulinum Neurotoxin E (Q27651362)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Structure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain complexed with small-molecule inhibitors highlight active-site flexibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Protein production by auto-induction in high density shaking cultures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Folding intermediates of SNARE complex assembly

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Mechanism of action of tetanus and botulinum neurotoxins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Conformational sampling of the botulinum neurotoxin serotype A light chain: implications for inhibitor binding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Development of Potent Inhibitors of Botulinum Neurotoxin Type B

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Neurotoxins affecting neuroexocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Efficacy of a novel metalloprotease inhibitor on botulinum neurotoxin B activity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533769

Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Structure of botulinum neurotoxin type D light chain at 1.65 A resolution: repercussions for VAMP-2 substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Substrate recognition strategy for botulinum neurotoxin serotype A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Cloning, high level expression, purification, and crystallization of the full length Clostridium botulinum neurotoxin type E light chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Unique substrate recognition by botulinum neurotoxins serotypes A and E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Partial protection against Botulinum B neurotoxin-induced blocking of exocytosis by a potent inhibitor of its metallopeptidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Rhodanine derivatives as selective protease inhibitors against bacterial toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Small tripeptide surrogates with low nanomolar affinity as potent inhibitors of the botulinum neurotoxin B metallo-proteolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Botulinum neurotoxin serotype F: identification of substrate recognition requirements and development of inhibitors with low nanomolar affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Multiple Pocket Recognition of SNAP25 by Botulinum Neurotoxin Serotype E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803756200

Purification and amino acid composition of type E botulinum neurotoxin

21 January 2018

1 reference

12 December 2020

Amino acid composition of Clostridium botulinum type F neurotoxin

1 reference

12 December 2020

Partial amino acid sequences of the heavy and light chains of botulinum neurotoxin type E

1 reference

12 December 2020

Structural analysis of botulinum neurotoxin serotype F light chain: implications on substrate binding and inhibitor design

1 reference

12 December 2020

A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease

1 reference

12 December 2020