Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators (Q27652258)

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14 January 2020

title

Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators (English)

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14 January 2020

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10

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14 January 2020

author name string

Casey E Bohl

1

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14 January 2020

Zengru Wu

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14 January 2020

Jiyun Chen

3

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14 January 2020

Michael L Mohler

4

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14 January 2020

Jun Yang

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14 January 2020

Dong Jin Hwang

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14 January 2020

Suni Mustafa

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Duane D Miller

8

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Charles E Bell

9

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14 January 2020

language of work or name

English

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publication date

5 September 2008

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Bioorganic & Medicinal Chemistry Letters

14 January 2020

published in

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volume

18

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issue

20

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page(s)

5567-5570

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Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats

14 January 2020

cites work

1 reference

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Structural basis for antagonism and resistance of bicalutamide in prostate cancer

20 March 2017

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Chiral nonsteroidal affinity ligands for the androgen receptor. 1. Bicalutamide analogues bearing electrophilic groups in the B aromatic ring

20 March 2017

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Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging

20 March 2017

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In vitro and in vivo structure-activity relationships of novel androgen receptor ligands with multiple substituents in the B-ring

29 September 2017

1 reference

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Structural basis for accommodation of nonsteroidal ligands in the androgen receptor

29 September 2017

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Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats

29 September 2017

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The para substituent of S-3-(phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides is a major structural determinant of in vivo disposition and activity of selective androgen receptor modulators

29 September 2017

1 reference

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Androgen replacement therapy: present and future

29 September 2017

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Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia.

29 September 2017

1 reference

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A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor

29 September 2017

1 reference

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Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators

29 September 2017

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Testosterone supplementation: what and how to give

29 September 2017

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An integrative review on current evidence of testosterone replacement therapy for the andropause

29 September 2017

1 reference

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Pharmacodynamics of selective androgen receptor modulators

29 September 2017

1 reference

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Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

29 September 2017

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Discovery of nonsteroidal androgens

29 September 2017

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Long-term pharmacokinetics of transdermal testosterone gel in hypogonadal men.

29 September 2017

1 reference

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Should the nonaromatizable androgen dihydrotestosterone be considered as an alternative to testosterone in the treatment of the andropause?

2 June 2018

1 reference

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Enantioselective binding of Casodex to the androgen receptor

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18805694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2008.09.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18805694%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

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14 January 2020

PubMed publication ID

18805694

1 reference