Rational stabilization of enzymes by computational redesign of surface charge-charge interactions (Q27653671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Rational stabilization of enzymes by computational redesign of surface charge-charge interactions (English)

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20 January 2020

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1

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20 January 2020

author name string

Mayank M Patel

2

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20 January 2020

Jiajing Liu

3

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20 January 2020

Scott A McCallum

4

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20 January 2020

Chunyu Wang

5

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20 January 2020

George I Makhatadze

6

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20 January 2020

language of work or name

English

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publication date

5 February 2009

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Proceedings of the National Academy of Sciences of the United States of America

20 January 2020

published in

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20 January 2020

volume

106

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20 January 2020

issue

8

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20 January 2020

page(s)

2601-2606

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The Pfam protein families database

20 January 2020

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20 March 2017

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20 March 2017

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20 March 2017

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Removal of surface charge-charge interactions from ubiquitin leaves the protein folded and very stable

20 March 2017

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Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

20 March 2017

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Insights into acylphosphatase structure and catalytic mechanism

20 March 2017

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20 March 2017

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On the relationship between thermal stability and catalytic power of enzymes

7 April 2017

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Computational design of the Fyn SH3 domain with increased stability through optimization of surface charge charge interactions

29 September 2017

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Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences.

29 September 2017

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Effects of charge-to-alanine substitutions on the stability of ribosomal protein L30e from Thermococcus celer.

29 September 2017

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Electrostatics in computational protein design

29 September 2017

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Cdc42: new roads to travel

29 September 2017

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A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins

29 September 2017

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Combining conformational flexibility and continuum electrostatics for calculating pK(a)s in proteins

29 September 2017

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29 September 2017

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THEMATICS: a simple computational predictor of enzyme function from structure

29 September 2017

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29 September 2017

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To charge or not to charge?

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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21 January 2018

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Mechanism of thermostabilization in a designed cold shock protein with optimized surface electrostatic interactions.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Protein stabilization by the rational design of surface charge-charge interactions

21 January 2018

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Aromatic acyl phosphates as substrates of acyl phosphatase

21 January 2018

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12 December 2020

Calculation of electrostatic interactions in proteins

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12 December 2020

Fluoride activation of the Rho family GTP-binding protein Cdc42Hs

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12 December 2020

Thermal versus guanidine-induced unfolding of ubiquitin. An analysis in terms of the contributions from charge-charge interactions to protein stability

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12 December 2020

Rational Modification of Protein Stability by the Mutation of Charged Surface Residues†

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12 December 2020

Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0808220106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

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20 January 2020

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