Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism (Q27658021)

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11 February 2020

title

Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism (English)

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Mycobacterium tuberculosis

11 February 2020

main subject

cell biology

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author

Geoff P Horsman

4

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11 February 2020

Lindsay D. Eltis

7

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11 February 2020

6

Edith Sim

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11 February 2020

author name string

Nathan A Lack

1

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11 February 2020

Katherine C Yam

2

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11 February 2020

Edward D Lowe

3

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11 February 2020

Robin L Owen

5

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11 February 2020

language of work or name

English

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publication date

29 October 2009

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Journal of Biological Chemistry

11 February 2020

published in

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11 February 2020

volume

285

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11 February 2020

issue

1

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11 February 2020

page(s)

434-443

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Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

11 February 2020

cites work

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Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis

20 March 2017

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Structure of HsaD, a steroid-degrading hydrolase, fromMycobacterium tuberculosis

20 March 2017

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The molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerization

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The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad

20 March 2017

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Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase

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20 March 2017

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20 March 2017

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21 January 2018

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Mycobacterial persistence requires the utilization of host cholesterol

20 March 2017

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A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages

20 March 2017

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Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages

20 March 2017

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Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment

20 March 2017

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Characterization of a C-C bond hydrolase from Sphingomonas wittichii RW1 with novel specificities towards polychlorinated biphenyl metabolites.

20 March 2017

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Structural changes in the L photointermediate of bacteriorhodopsin

29 September 2017

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Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway.

29 September 2017

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Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice.

29 September 2017

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THE ASSIMILATION OF CHOLESTEROL BY MYCOBACTERIUM SMEGMATIS.

29 September 2017

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Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236.

29 September 2017

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29 September 2017

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Purification, characterization, and stereochemical analysis of a C-C hydrolase: 2-hydroxy-6-keto-nona-2,4-diene-1,9-dioic acid 5,6-hydrolase

29 September 2017

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Crystal structure of 2-hydroxyl-6-oxo-6-phenylhexa-2,4-dienoic acid (HPDA) hydrolase (BphD enzyme) from the Rhodococcus sp. strain RHA1 of the PCB degradation pathway

29 September 2017

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21 January 2018

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12 December 2020

Catalytic promiscuity in the alpha/beta-hydrolase superfamily: hydroxamic acid formation, C--C bond formation, ester and thioester hydrolysis in the C--C hydrolase family

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12 December 2020

Catalytic mechanism of a C-C hydrolase enzyme: evidence for a gem-diol intermediate, not an acyl enzyme

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Combined directed ortho Metalation/Suzuki-Miyaura cross-coupling strategies. Regiospecific synthesis of chlorodihydroxybiphenyls and polychlorinated biphenyls

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The predischarge chromophore in bacteriorhodopsin: a 15N solid-state NMR study of the L photointermediate

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The binding of cytochrome c peroxidase and ferricytochrome c. A spectrophotometric determination of the equilibrium association constant as a function of ionic strength

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Identifiers

DOI

10.1074/JBC.M109.058081

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19875455%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

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11 February 2020

PubMed publication ID

19875455

2 references