The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity (Q27658866)

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16 January 2020

title

The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity (English)

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16 January 2020

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4

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16 January 2020

author name string

Iain S Macpherson

1

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16 January 2020

Sivapriya Kirubakaran

2

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16 January 2020

Suresh Kumar Gorla

3

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16 January 2020

J Alejandro D'Aquino

5

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16 January 2020

Minjia Zhang

6

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16 January 2020

Gregory D Cuny

7

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16 January 2020

Lizbeth Hedstrom

8

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16 January 2020

language of work or name

English

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publication date

1 February 2010

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Journal of the American Chemical Society

16 January 2020

published in

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16 January 2020

volume

132

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16 January 2020

issue

4

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16 January 2020

page(s)

1230-1231

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IMP dehydrogenase: structure, mechanism, and inhibition

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819028

The genome of Cryptosporidium hominis

20 March 2017

1 reference

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Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum

20 March 2017

1 reference

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Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6

20 March 2017

1 reference

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Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

20 March 2017

1 reference

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Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

20 March 2017

1 reference

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Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis

29 September 2017

1 reference

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An updated review on Cryptosporidium and Giardia

29 September 2017

1 reference

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Cryptosporidium: a water-borne zoonotic parasite

29 September 2017

1 reference

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Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design

29 September 2017

1 reference

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Gene transfer in the evolution of parasite nucleotide biosynthesis

29 September 2017

1 reference

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Genetic complementation in apicomplexan parasites

29 September 2017

1 reference

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The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819028

A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases

29 September 2017

1 reference

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2 June 2018

Identifiers

DOI

10.1021/JA909947A

1 reference

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16 January 2020

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16 January 2020

PubMed publication ID

20052976

1 reference