Structural Basis for Conformational Dynamics of GTP-bound Ras Protein (Q27661719)

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2 February 2020

title

Structural basis for conformational dynamics of GTP-bound Ras protein (English)

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2 February 2020

Atsuo Tamura

13

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2 February 2020

author name string

Fumi Shima

1

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2 February 2020

Yuichi Ijiri

2

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Shin Muraoka

3

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Jingling Liao

4

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2 February 2020

Min Ye

5

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2 February 2020

Mitsugu Araki

6

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Kousuke Matsumoto

7

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Naoki Yamamoto

8

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Takeshi Sugimoto

9

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Yoko Yoshikawa

10

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Masaki Yamamoto

12

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Tohru Kataoka

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language of work or name

English

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publication date

17 May 2010

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2 February 2020

number of pages

10

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Journal of Biological Chemistry

inferred from page(s)

published in

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volume

285

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issue

29

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2 February 2020

page(s)

22696-22705

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Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding

2 February 2020

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Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42

20 March 2017

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Dynamic properties of the Ras switch I region and its importance for binding to effectors

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

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Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

20 March 2017

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M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6

20 March 2017

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Structural basis for the interaction of Ras with RalGDS

20 March 2017

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Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

20 March 2017

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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The guanine nucleotide-binding switch in three dimensions

20 March 2017

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Targeting RAS signalling pathways in cancer therapy

20 March 2017

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Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

20 March 2017

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20 March 2017

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Characterization of a Ras mutant with identical GDP- and GTP-bound structures

7 April 2017

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Crystal structure of M-Ras reveals a GTP-bound "off" state conformation of Ras family small GTPases.

29 September 2017

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29 September 2017

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Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics

21 January 2018

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Perturbation of the conformational equilibria in Ras by selective mutations as studied by 31P NMR spectroscopy

21 January 2018

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21 January 2018

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Structure of the G60A mutant of Ras: implications for the dominant negative effect

21 January 2018

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Conformational states of the nuclear GTP-binding protein Ran and its complexes with the exchange factor RCC1 and the effector protein RanBP1

21 January 2018

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12 December 2020

Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPgammaS

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12 December 2020

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High frequency (139.5 GHz) electron paramagnetic resonance spectroscopy of the GTP form of p21 ras with selective 17O labeling of threonine

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.125161

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