Intermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESY (Q27661869)

2

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Einat Schnur

3

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Zohar Biron

4

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Rina Levy

5

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Yingqi Xu

6

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Daiwen Yang

7

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Jacob Anglister

Solution Nuclear Magnetic Resonance Structure of Membrane-Integral Diacylglycerol Kinase

8

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language of work or name

English

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publication date

29 June 2010

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published in

Biochemistry

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volume

49

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issue

25

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page(s)

5117-33

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cites work

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NMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsA

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Structural basis for the selectivity of the external thioesterase of the surfactin synthetase

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Solution NMR Structure of Selenium-binding Protein from Methanococcus vannielii

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Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal Coordinates

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Structure of an atypical orphan response regulator protein supports a new phosphorylation-independent regulatory mechanism

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Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

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The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding

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Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family

20 March 2017

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The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site

20 March 2017

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Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr

20 March 2017

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Structure and mutagenesis of the Dbl homology domain

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Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

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The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution

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Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

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The crystal structure of human interferon beta at 2.2-A resolution

20 March 2017

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Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

20 March 2017

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The human interferon alpha/beta receptor: characterization and molecular cloning

20 March 2017

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NMR View: A computer program for the visualization and analysis of NMR data

20 March 2017

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Version 1.2 of the Crystallography and NMR system

20 March 2017

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Inference of macromolecular assemblies from crystalline state

20 March 2017

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HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

20 March 2017

1 reference

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How cells respond to interferons

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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MOLMOL: a program for display and analysis of macromolecular structures

20 March 2017

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

1 reference

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

20 March 2017

1 reference

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The receptor of the type I interferon family

20 March 2017

1 reference

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Interferons, interferon-like cytokines, and their receptors

20 March 2017

1 reference

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Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B

20 March 2017

1 reference

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Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2

20 March 2017

1 reference

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Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

20 March 2017

1 reference

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Evaluating protein structures determined by structural genomics consortia

20 March 2017

1 reference

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Unraveling hot spots in binding interfaces: progress and challenges

7 April 2017

1 reference

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Automated analysis of interatomic contacts in proteins

7 April 2017

1 reference

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An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types.

7 April 2017

1 reference

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NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site

29 September 2017

1 reference

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Type I interferon receptors: biochemistry and biological functions.

29 September 2017

1 reference

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Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex

29 September 2017

1 reference

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Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex.

29 September 2017

1 reference

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Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives

29 September 2017

1 reference

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NMR studies of protein structure and dynamics

29 September 2017

1 reference

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Solution NMR-derived global fold of a monomeric 82-kDa enzyme

29 September 2017

1 reference

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Charged gels as orienting media for measurement of residual dipolar couplings in soluble and integral membrane proteins.

29 September 2017

1 reference

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Nuclear magnetic resonance spectroscopy of high-molecular-weight proteins.

29 September 2017

1 reference

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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.

29 September 2017

1 reference

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Cancer immunotherapy: the interferon-alpha experience

29 September 2017

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The human interferon receptor: NMR-based modeling, mapping of the IFN-alpha 2 binding site, and observed ligand-induced tightening

29 September 2017

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Peginterferon-alpha-2a (40 kD): a review of its use in the management of chronic hepatitis C.

29 September 2017

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Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking

29 September 2017

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Interferons alpha and beta as immune regulators--a new look

29 September 2017

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New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface

29 September 2017

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Biophysical analysis of the interaction of human ifnar2 expressed in E. coli with IFNalpha2.

29 September 2017

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Shared receptor components but distinct complexes for alpha and beta interferons

29 September 2017

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The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association

29 September 2017

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Refined solution structure and backbone dynamics of HIV-1 Nef.

29 September 2017

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Use of deuterium labeling in NMR: overcoming a sizeable problem

29 September 2017

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Alpha and beta interferons and their receptor and their friends and relations.

29 September 2017

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Use of deuterium labelling in NMR studies of antibody combining site structure

29 September 2017

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Heteronuclear filters in two-dimensional [1H,1H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

29 September 2017

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The solution structures of Escherichia coli trp repressor and trp aporepressor at an intermediate resolution.

29 September 2017

1 reference

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NMR structures of proteins and protein complexes beyond 20,000 M(r).

29 September 2017

1 reference

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Conformation of the principal neutralizing determinant of human immunodeficiency virus type 1 in complex with an anti-gp120 virus neutralizing antibody studied by two-dimensional nuclear magnetic resonance difference spectroscopy

2 June 2018

1 reference

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A T1 rho-filtered two-dimensional transferred NOE spectrum for studying antibody interactions with peptide antigens

2 June 2018

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Modeling studies of the change in conformation required for cleavage of limited proteolytic sites

2 June 2018

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Probing antibody diversity by 2D NMR: comparison of amino acid sequences, predicted structures, and observed antibody-antigen interactions in complexes of two antipeptide antibodies

2 June 2018

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Sequence-specific 1H NMR assignments and secondary structure in solution of Escherichia coli trp repressor

2 June 2018

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Substrate recognition by proteinases

2 June 2018

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Improved 1HN-detected triple resonance TROSY-based experiments.

2 June 2018

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Suppression of anti-TROSY lines in a sensitivity enhanced gradient selection TROSY scheme.

27 November 2018

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Side-chain assignments of methyl-containing residues in a uniformly 13C-labeled hemoglobin in the carbonmonoxy form.

27 November 2018

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Sequence-specific assignments of methyl groups in high-molecular weight proteins

27 November 2018

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A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes

27 November 2018

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Dimerization and signal transduction of the growth hormone receptor

27 November 2018

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Longitudinal (1)H relaxation optimization in TROSY NMR spectroscopy.

27 November 2018

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An approach for high-throughput structure determination of proteins by NMR spectroscopy.

27 November 2018

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Application of amino acid type-specific 1H- and 14N-labeling in a 2H-, 15N-labeled background to a 47 kDa homodimer: potential for NMR structure determination of large proteins.

27 November 2018

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Global Folds of Highly Deuterated, Methyl-Protonated Proteins by Multidimensional NMR†

27 November 2018

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Selective Methyl Group Protonation of Perdeuterated Proteins

27 November 2018

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Structural and mutational analysis of affinity-inert contact residues at the growth hormone-receptor interface

27 November 2018

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A new strategy for structure determination of large proteins in solution without deuteration

27 November 2018

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Erythropoietin receptor activation by a ligand-induced conformation change

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12 December 2020

Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity

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12 December 2020

A General Strategy for the Assignment of Aliphatic Side-Chain Resonances of Uniformly13C,15N-Labeled Large Proteins

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12 December 2020

NMR observation of interactions in the combining site region of an antibody using a spin-labeled peptide antigen and NOESY difference spectroscopy

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12 December 2020

Interactions of antibody aromatic residues with a peptide of cholera toxin observed by two-dimensional transferred nuclear Overhauser effect difference spectroscopy

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12 December 2020

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12 December 2020

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