A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutants (Q27662051)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Wai Kwan Tang

1

0 references

Dongyang Li

2

0 references

Chou-chi Li

3

0 references

Lothar Esser

4

0 references

Renming Dai

5

0 references

Liang Guo

6

0 references

Di Xia

The crystal structure of murine p97/VCP at 3.6A

7

0 references

language of work or name

English

0 references

publication date

7 July 2010

0 references

published in

The EMBO Journal

0 references

volume

29

0 references

issue

13

0 references

page(s)

2217-29

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Structure of the AAA ATPase p97

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Likelihood-enhanced fast rotation functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

The interpretation of protein structures: Estimation of static accessibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

20 March 2017

https://api.crossref.org/works/10.1038/EMBOJ.2010.104

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Conformational changes in the AAA ATPase p97-p47 adaptor complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Nucleotide dependent motion and mechanism of action of p97/VCP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

The use of blue native PAGE in the evaluation of membrane protein aggregation states for crystallization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Pathological consequences of VCP mutations on human striated muscle.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905243

Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

A novel mutation in the VCP gene (G157R) in a German family with inclusion-body myopathy with Paget disease of bone and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

Two Australian families with inclusion-body myopathy, Paget's disease of bone and frontotemporal dementia: novel clinical and genetic findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

Mutant valosin-containing protein causes a novel type of frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.104

p97, a protein coping with multiple identities

21 January 2018

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

Going through the motions: The ATPase cycle of p97

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Low-affinity binding determined by titration calorimetry using a high-affinity coupling ligand: a thermodynamic study of ligand binding to protein tyrosine phosphatase 1B

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2010.104

1 reference

2617157

2617157

1 reference

1 reference

1 reference