Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses (Q27663966)

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9 February 2020

title

Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses (English)

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9 February 2020

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9 February 2020

Susan A. Barrett

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9 February 2020

Thomas S. Peat

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Janet Newman

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Jennifer McKimm-Breschkin

9 February 2020

9

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Victor A Streltsov

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9 February 2020

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Takehiko Saito

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author name string

Lynne Waddington

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Masato Tashiro

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language of work or name

English

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publication date

1 September 2010

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Journal of Medicinal Chemistry

9 February 2020

published in

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volume

53

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issue

17

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page(s)

6421-6431

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Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

9 February 2020

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Rational design of potent sialidase-based inhibitors of influenza virus replication

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Detection of the rapid emergence of the H275Y mutation associated with oseltamivir resistance in severe pandemic influenza virus A/H1N1 09 infections.

7 April 2017

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Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

29 September 2017

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29 September 2017

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Neuraminidase inhibitor resistance after oseltamivir treatment of acute influenza A and B in children

29 September 2017

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Pharmacokinetics of high-dose oseltamivir in healthy volunteers

29 September 2017

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29 September 2017

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Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors

29 September 2017

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29 September 2017

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29 September 2017

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Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.

29 September 2017

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Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors

29 September 2017

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Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.

29 September 2017

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Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en

29 September 2017

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29 September 2017

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Structure of influenza virus neuraminidase B/Lee/40 complexed with sialic acid and a dehydro analog at 1.8-A resolution: implications for the catalytic mechanism

29 September 2017

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Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution

29 September 2017

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Structure of the catalytic and antigenic sites in influenza virus neuraminidase

29 September 2017

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29 September 2017

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GS4071 is a slow-binding inhibitor of influenza neuraminidase from both A and B strains

2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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27 November 2018

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Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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2,3-didehydro-2,4-dideoxy-4-guanidino-N-acetyl-D-neuraminic acid (4-guanidino-Neu5Ac2en) is a slow-binding inhibitor of sialidase from both influenza A virus and influenza B virus

27 November 2018

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Comparison of Structure and Sequence of Influenza B/Yamagata and B/Beijing Neuraminidases Shows a Conserved "Head" but Much Greater Variability in the "Stalk" and NB Protein

27 November 2018

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27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20695427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM100621S

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20695427%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20695427%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20695427

1 reference