Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies (Q27665884)

2

0 references

Sophia Rits-Volloch

3

0 references

Michael M Freeman

4

0 references

Susan Zolla-Pazner

5

0 references

Bing Chen

Nature Structural & Molecular Biology

6

0 references

publication date

December 2010

0 references

published in

0 references

volume

17

0 references

page(s)

1486-91

0 references

issue

12

0 references

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

7 April 2017

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7 April 2017

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Electron-density map interpretation

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

7 April 2017

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

7 April 2017

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

7 April 2017

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

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inferred from DOI database lookup

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based on heuristic

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Role of HIV membrane in neutralization by two broadly neutralizing antibodies

29 September 2017

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29 September 2017

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29 September 2017

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An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10

29 September 2017

1 reference

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29 September 2017

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Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

29 September 2017

1 reference

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

29 September 2017

1 reference

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Novel therapies based on mechanisms of HIV-1 cell entry.

29 September 2017

1 reference

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Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein

29 September 2017

1 reference

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A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Recognition by human monoclonal antibodies of free and complexed peptides representing the prefusogenic and fusogenic forms of human immunodeficiency virus type 1 gp41

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41

29 September 2017

1 reference

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Antibody-dependent cellular cytotoxicity directed against cells expressing human immunodeficiency virus type 1 envelope of primary or laboratory-adapted strains by human and chimpanzee monoclonal antibodies of different epitope specificities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Generation of human monoclonal antibodies to human immunodeficiency virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Functional activities of 20 human immunodeficiency virus type 1 (HIV-1)-specific human monoclonal antibodies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Kinetic dependence to HIV-1 entry inhibition

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Effects of oligomerization on the epitopes of the human immunodeficiency virus type 1 envelope glycoproteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997185

Mechanism of membrane fusion by viral envelope proteins

27 November 2018

1 reference

Crossref

Neutralization of HIV-1 primary isolates by polyclonal and monoclonal human antibodies

31 March 2020

1 reference

Crossref

PROCHECK: a program to check the stereochemical quality of protein structures

31 March 2020

1 reference

Crossref

Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21076402

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.1950

1 reference

Dimensions Publication ID

3789111

1031581624

0 references

3789111

1 reference

1 reference

1 reference