Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design (Q27665912)

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scientific article published on November 16, 2010

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English	Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design	scientific article published on November 16, 2010

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Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design (English)

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allosteric inhibitor

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Kunchithapadam Swaminathan

9

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Suguna Badireddy

1

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Gao Yunfeng

2

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Mark Ritchie

3

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Pearl Akamine

4

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Jian Wu

5

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Lin Qingsong

8

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Choel W. Kim

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081668

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Susan S. Taylor

7

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Ganesh S. Anand

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March 2011

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16 November 2010

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https://www.mcponline.org/content/mcprot/10/3/M110.004390.full.pdf

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http://www.mcponline.org/cgi/reprint/10/3/M110.004390.pdf

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http://www.mcponline.org/cgi/content/full/10/3/M110.004390

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http://www.mcponline.org/cgi/content/abstract/10/3/M110.004390

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081668/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081668/?tool=EBI

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28 August 2024

https://europepmc.org/articles/PMC3047156

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081668

28 August 2024

https://europepmc.org/articles/PMC3047156?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081668

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https://doi.org/10.1074/mcp.m110.004390

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081668

28 August 2024

https://api.elsevier.com/content/article/PII:S1535947620325135?httpAccept=text/xml

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10.1074/MCP.M110.004390

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28 August 2024

https://api.elsevier.com/content/article/PII:S1535947620325135?httpAccept=text/plain

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10.1074/MCP.M110.004390

https://api.crossref.org/works/10.1074/MCP.M110.004390

28 August 2024

https://syndication.highwire.org/content/doi/10.1074/mcp.M110.004390

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10.1074/MCP.M110.004390

https://api.crossref.org/works/10.1074/MCP.M110.004390

28 August 2024

Molecular & Cellular Proteomics

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10

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3

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M110.004390

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High-speed and high-resolution UPLC separation at zero degrees Celsius

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20 March 2017

PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

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Structure and regulation of the cAMP-binding domains of Epac2

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Cyclic AMP- and (Rp)-cAMPS-induced conformational changes in a complex of the catalytic and regulatory (RI{alpha}) subunits of cyclic AMP-dependent protein kinase.

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Label-free quantitative proteomics analysis of etiolated maize seedling leaves during greening

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Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A.

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Deletion of cAMP-binding site B in the regulatory subunit of cAMP-dependent protein kinase alters the photoaffinity labeling of site A.

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1 reference

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1 reference

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51

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10.1074/MCP.M110.004390

https://api.crossref.org/works/10.1074/MCP.M110.004390

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