Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY (Q27666573)

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English	Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY	scientific article

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scholarly article

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Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY (English)

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crystal structure

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Marie-France Langelier

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Marie-France Langelier

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4

object named as

John M Pascal

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author name string

Jamie L Planck

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Swati Roy

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language of work or name

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publication date

25 March 2011

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Journal of Biological Chemistry

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286

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12

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10690-701

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A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

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20 March 2017

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

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Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif

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20 March 2017

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

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20 March 2017

The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining

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20 March 2017

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

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Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

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PARP inhibition: PARP1 and beyond

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7 April 2017

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

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29 September 2017

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction

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29 September 2017

Uncoupling of the transactivation and transrepression functions of PARP1 protein

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29 September 2017

Structural and biophysical studies of human PARP-1 in complex with damaged DNA.

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29 September 2017

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

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Parthanatos, a messenger of death

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29 September 2017

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

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29 September 2017

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

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29 September 2017

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

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29 September 2017

Poly(ADP-ribose) (PAR) polymer is a death signal

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29 September 2017

X-ray structure of a tetranucleosome and its implications for the chromatin fibre

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Sensing DNA damage by PARP-like fingers

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29 September 2017

Poly(ADP-ribose) polymerase-1 dimerizes at a 5' recessed DNA end in vitro: a fluorescence study.

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29 September 2017

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

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29 September 2017

DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

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29 September 2017

Minor groove-binding architectural proteins: structure, function, and DNA recognition.

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Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

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29 September 2017

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

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29 September 2017

The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.

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2 June 2018

New functions for an ancient domain.

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21 January 2018

A nick-sensing DNA 3'-repair enzyme from Arabidopsis.

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21 January 2018

Regulation of poly(ADP-ribose) polymerase-1 by DNA structure-specific binding

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21 January 2018

The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription

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21 January 2018

Solution structure and DNA binding of the zinc-finger domain from DNA ligase IIIalpha

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21 January 2018

Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase

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21 January 2018

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

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21 January 2018

DNA-induced dimerization of poly(ADP-ribose) polymerase-1 triggers its activation

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based on heuristic

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ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA

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https://pubmed.ncbi.nlm.nih.gov/21233213

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based on heuristic

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