Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution (Q27666652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248202%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution (English)

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20 January 2020

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20 January 2020

Carl J. Mousley

3

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20 January 2020

Peihua Yuan

5

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20 January 2020

Eric A. Ortlund

12

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20 January 2020

author name string

Marek Dynowski

2

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20 January 2020

Sweety D Shah

4

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20 January 2020

Eva M Winklbauer

6

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20 January 2020

Marília K F de Campos

7

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20 January 2020

Kyle Trettin

8

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20 January 2020

Mary-Chely Quinones

9

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20 January 2020

Tatyana I Smirnova

10

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20 January 2020

Lora L Yanagisawa

11

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20 January 2020

Vytas A Bankaitis

13

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20 January 2020

publication date

19 January 2011

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Molecular Biology of the Cell

20 January 2020

published in

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20 January 2020

volume

22

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20 January 2020

issue

6

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20 January 2020

page(s)

892-905

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Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily

20 January 2020

cites work

1 reference

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20 March 2017

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Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein

20 March 2017

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Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.

20 March 2017

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Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology

20 March 2017

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Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth

20 March 2017

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Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.

20 March 2017

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Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy

20 March 2017

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SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

20 March 2017

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Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

20 March 2017

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An essential role for a phospholipid transfer protein in yeast Golgi function

20 March 2017

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Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein

20 March 2017

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Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

20 March 2017

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Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects

20 March 2017

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Membrane recognition by phospholipid-binding domains

20 March 2017

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Phosphoinositide kinases

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Zebrafish class 1 phosphatidylinositol transfer proteins: PITPbeta and double cone cell outer segment integrity in retina.

7 April 2017

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The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling

29 September 2017

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Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae

29 September 2017

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Conformational dynamics of the major yeast phosphatidylinositol transfer protein sec14p: insight into the mechanisms of phospholipid exchange and diseases of sec14p-like protein deficiencies

29 September 2017

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Local polarity and hydrogen bonding inside the Sec14p phospholipid-binding cavity: high-field multi-frequency electron paramagnetic resonance studies

29 September 2017

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Crystallization and preliminary X-ray diffraction analysis of phospholipid-bound Sfh1p, a member of the Saccharomyces cerevisiae Sec14p-like phosphatidylinositol transfer protein family

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Ultra-stable temperature control in EPR experiments: thermodynamics of gel-to-liquid phase transition in spin-labeled phospholipid bilayers and bilayer perturbations by spin labels.

27 November 2018

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A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein.

27 November 2018

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Mutations in a novel gene encoding a CRAL-TRIO domain cause human Cayman ataxia and ataxia/dystonia in the jittery mouse.

27 November 2018

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27 November 2018

Identifiers

DOI

10.1091/MBC.E10-11-0903

1 reference

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20 January 2020

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20 January 2020

PubMed publication ID

21248202

1 reference