Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme (Q27666879)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300294%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300294%20AND%20SRC:MED&resulttype=core&format=json

Protein kinase, cAMP dependent, catalytic, alpha

21 January 2020

main subject

structural biology

0 references

1 reference

GOA release 2020-03-11

author

Donald K Blumenthal

8

1 reference

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21 January 2020

Alexandr P Kornev

9

1 reference

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21 January 2020

author name string

Angela J Boettcher

1

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21 January 2020

Jian Wu

2

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21 January 2020

Choel Kim

3

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21 January 2020

Jie Yang

4

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21 January 2020

Jessica Bruystens

5

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21 January 2020

Nikki Cheung

6

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21 January 2020

Juniper K Pennypacker

7

1 reference

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21 January 2020

Susan S Taylor

10

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21 January 2020

publication date

1 February 2011

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21 January 2020

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21 January 2020

volume

19

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21 January 2020

issue

2

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21 January 2020

page(s)

265-276

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Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity

21 January 2020

cites work

1 reference

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Novel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme Structures

20 March 2017

1 reference

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PKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform Diversity

20 March 2017

1 reference

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PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

20 March 2017

1 reference

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SuperPose: a simple server for sophisticated structural superposition

20 March 2017

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Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure

20 March 2017

1 reference

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Structure and regulation of the cAMP-binding domains of Epac2

20 March 2017

1 reference

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Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase

20 March 2017

1 reference

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Determination of domain structure of proteins from X-ray solution scattering

20 March 2017

1 reference

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Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit

20 March 2017

1 reference

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Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

20 March 2017

1 reference

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

20 March 2017

1 reference

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Inference of macromolecular assemblies from crystalline state

20 March 2017

1 reference

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A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

20 March 2017

1 reference

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Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

20 March 2017

1 reference

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Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097484

Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations.

7 April 2017

1 reference

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Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering.

29 September 2017

1 reference

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A helix scaffold for the assembly of active protein kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097484

Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A.

29 September 2017

1 reference

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Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix

29 September 2017

1 reference

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Probing the multidomain structure of the type I regulatory subunit of cAMP-dependent protein kinase using mutational analysis: role and environment of endogenous tryptophans

2 June 2018

1 reference

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Backbone flexibility of five sites on the catalytic subunit of cAMP-dependent protein kinase in the open and closed conformations

2 June 2018

1 reference

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Expression and mutagenesis of the regulatory subunit of cAMP-dependent protein kinase in Escherichia coli

2 June 2018

1 reference

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Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms

2 June 2018

1 reference

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2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor

27 November 2018

1 reference

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Differential effects of substrate on type I and type II PKA holoenzyme dissociation

27 November 2018

1 reference

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Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions

27 November 2018

1 reference

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C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change

27 November 2018

1 reference

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Consequences of cAMP and catalytic-subunit binding on the flexibility of the A-kinase regulatory subunit

27 November 2018

1 reference

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Differential binding of cAMP-dependent protein kinase regulatory subunit isoforms Ialpha and IIbeta to the catalytic subunit

27 November 2018

1 reference

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Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formation

27 November 2018

1 reference

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Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: characterization of the sites by mutagenesis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21300294

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2010.12.005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300294%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

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21 January 2020

PubMed publication ID

21300294

1 reference