Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase (Q27666972)

ChEBI release 2020-05-28

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5

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author name string

Gesa Volkers

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Gottfried J Palm

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Manfred S Weiss

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Gerard D Wright

Functional, biophysical, and structural bases for antibacterial activity of tigecycline

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language of work or name

English

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publication date

6 April 2011

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published in

FEBS Letters

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volume

585

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issue

7

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page(s)

1061-6

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cites work

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Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii

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TetX is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics

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Tigecycline is modified by the flavin-dependent monooxygenase TetX.

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The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

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Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline

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Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

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A robust platform for the synthesis of new tetracycline antibiotics

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