Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant (Q27667926)

8

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Stephen G. Bell

object named as

Stephen G Bell

6

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Rao Zihe

9

object named as

Zihe Rao

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author name string

Christopher J C Whitehouse

1

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Wen Yang

2

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Jake A Yorke

3

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Henry G Tufton

4

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Lydia C I Ogilvie

5

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Weihong Zhou

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Luet-Lok Wong

Cytosine deaminase gene as a positive selection marker

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language of work or name

English

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publication date

28 October 2011

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published in

Dalton Transactions

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volume

40

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issue

40

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page(s)

10383-96

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cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Residue size at position 87 of cytochrome P450 BM-3 determines its stereoselectivity in propylbenzene and 3-chlorostyrene oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Preparative use of isolated CYP102 monooxygenases -- a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Evolutionary history of a specialized p450 propane monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Rational design of a minimal and highly enriched CYP102A1 mutant library with improved regio-, stereo- and chemoselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

A highly active single-mutation variant of P450BM3 (CYP102A1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Finding better protein engineering strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

The role of Thr268 in oxygen activation of cytochrome P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Pivotal role of water in the mechanism of P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Novel haem co-ordination variants of flavocytochrome P450BM3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Oxygen activation and electron transfer in flavocytochrome P450 BM3

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

The thermodynamics and kinetics of electron transfer in the cytochrome P450cam enzyme system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Probing electron transfer in flavocytochrome P-450 BM3 and its component domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structure and function of cytochromes P450: a comparative analysis of three crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structure of a cytochrome P450-redox partner electron-transfer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structural rationalization of novel drug metabolizing mutants of cytochrome P450 BM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

A self-sufficient peroxide-driven hydroxylation biocatalyst

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Desaturation of alkylbenzenes by cytochrome P450(BM3) (CYP102A1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J

Identification of Critical Residues in Novel Drug Metabolizing Mutants of Cytochrome P450 BM3 Using Random Mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10098J