Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation (Q27670453)

10

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David Baker

object named as

David Baker

9

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author name string

Stuart A Sievers

1

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John Karanicolas

2

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Howard W Chang

3

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Anni Zhao

4

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Lin Jiang

5

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Onofrio Zirafi

6

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Jason T Stevens

7

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Jan Münch

Molecular mechanisms for protein-encoded inheritance

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language of work or name

English

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publication date

15 June 2011

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published in

Nature

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volume

475

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issue

7354

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page(s)

96-100

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cites work

1 reference

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Semen-derived amyloid fibrils drastically enhance HIV infection

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

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Structure of the cross-beta spine of amyloid-like fibrils

20 March 2017

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

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Shape complementarity at protein/protein interfaces

20 March 2017

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20 March 2017

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Alzheimer's disease: genes, proteins, and therapy

20 March 2017

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A primer of amyloid nomenclature

20 March 2017

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Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure

20 March 2017

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Unraveling hot spots in binding interfaces: progress and challenges

20 March 2017

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Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

7 April 2017

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Identifying the amylome, proteins capable of forming amyloid-like fibrils

7 April 2017

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Functional amyloids as natural storage of peptide hormones in pituitary secretory granules

29 September 2017

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The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection

29 September 2017

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Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth

29 September 2017

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Functional amyloid--from bacteria to humans.

29 September 2017

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Peptide-based inhibitors of amyloid assembly

29 September 2017

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N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure

29 September 2017

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Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

29 September 2017

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Prediction of nucleating sequences from amyloidogenic propensities of tau-related peptides

29 September 2017

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Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display

29 September 2017

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Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism

29 September 2017

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Peptide inhibitors of beta amyloid aggregation

29 September 2017

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Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

29 September 2017

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A nucleated assembly mechanism of Alzheimer paired helical filaments

29 September 2017

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Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

29 September 2017

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Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

29 September 2017

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The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

29 September 2017

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The X-ray interpretation of denaturation and the structure of the seed globulins

29 September 2017

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The formation of straight and twisted filaments from short tau peptides

2 June 2018

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Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution.

2 June 2018

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Amyloid fibril formation can proceed from different conformations of a partially unfolded protein

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10154

Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10154

Structure and orientation of peptide inhibitors bound to beta-amyloid fibrils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10154

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10154

Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073670

Computational redesign of protein-protein interaction specificity

27 November 2018

1 reference

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Labelling of peptides with 1.4-nm gold particles to demonstrate their binding sites in the rat spinal cord

27 November 2018

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12 December 2020

Arrest of beta-amyloid fibril formation by a pentapeptide ligand

1 reference

12 December 2020

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

1 reference

12 December 2020

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

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12 December 2020

Identifiers

DOI

10.1038/NATURE10154

1 reference

Dimensions Publication ID

991797

1052435615

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Fatcat ID

release_cjqre5jqm5ehvgnbq36mq36cli

0 references

991797

1 reference

1 reference

1 reference