Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A (Q27670633)

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English	Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A	scientific article

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Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A (English)

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4

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Marco Mazzorana

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Marco Mazzorana

2

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object named as

Mario A Pagano

6

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object named as

Giorgio Cozza

5

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Lorenzo A Pinna

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Lorenzo A Pinna

10

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Stefania Sarno

1

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author name string

Ryan Traynor

3

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Flavio Meggio

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Giuseppe Zagotto

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Roberto Battistutta

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publication date

February 2012

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Cellular and Molecular Life Sciences

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69

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3

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449-60

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The druggable genome

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The protein kinase complement of the human genome

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Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis

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Variable contribution of protein kinases to the generation of the human phosphoproteome: a global weblogo analysis

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Protein kinase CK2 in human diseases.

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Protein kinase CK2 as a druggable target

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Multiple myeloma cell survival relies on high activity of protein kinase CK2.

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Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.

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Non-oncogene addiction and the stress phenotype of cancer cells

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Emergence of protein kinase CK2 as a key target in cancer therapy

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A structural insight into CK2 inhibition

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21 January 2018

Protein kinase CK2 in health and disease: Structural bases of protein kinase CK2 inhibition

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The selectivity of inhibitors of protein kinase CK2: an update

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Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships

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Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

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Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

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The selectivity of protein kinase inhibitors: a further update

1 reference

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21 January 2018

Gini coefficient: a new way to express selectivity of kinase inhibitors against a family of kinases

1 reference

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21 January 2018

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

1 reference

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21 January 2018

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Features and development of Coot

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Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

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Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight

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Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease

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Protein kinase CK2--a key suppressor of apoptosis

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21 January 2018

Identification of Ellagic Acid as Potent Inhibitor of Protein Kinase CK2: A Successful Example of a Virtual Screening Application

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Protein Kinase CK2 Mutants Defective in Substrate Recognition

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Specificity determinants of substrate recognition by the protein kinase DYRK1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/21720886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CCP4 suite: programs for protein crystallography

1 reference

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inferred from PubMed ID database lookup

Endogenous phosphate acceptor proteins for rat liver cytosolic casein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21720886

12 December 2020

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inferred from PubMed ID database lookup

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10.1007/S00018-011-0758-7

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