Binding Mechanism of Metal⋅NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases (Q27670729)

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7 February 2020

title

Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases (English)

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7 February 2020

0 references

5

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James L. Keck

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Jue D Wang

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James M Berger

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7 February 2020

author name string

Richard U Rymer

1

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7 February 2020

Francisco A Solorio

2

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Ashley K Tehranchi

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7 February 2020

Clement Chu

4

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publication date

12 July 2012

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7 February 2020

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7 February 2020

volume

20

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issue

9

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7 February 2020

page(s)

1478-1489

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A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

7 February 2020

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20 March 2017

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20 March 2017

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20 March 2017

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Structure of the RNA polymerase domain of E. coli primase

20 March 2017

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20 March 2017

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

20 March 2017

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20 March 2017

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Features and development of Coot

20 March 2017

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20 March 2017

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(p)ppGpp: still magical?

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20 March 2017

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Control of bacterial transcription, translation and replication by (p)ppGpp

7 April 2017

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20 March 2017

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Single-molecule studies of the replisome

7 April 2017

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Timing, coordination, and rhythm: acrobatics at the DNA replication fork.

29 September 2017

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Allosteric regulation of the primase (DnaG) activity by the clamp-loader (tau) in vitro.

29 September 2017

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Single-molecule studies of fork dynamics in Escherichia coli DNA replication

29 September 2017

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FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studies

29 September 2017

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Nutritional control of elongation of DNA replication by (p)ppGpp

29 September 2017

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ppGpp: stringent response and survival.

29 September 2017

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DNA primase acts as a molecular brake in DNA replication

29 September 2017

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Acidic residues in the nucleotide-binding site of the bacteriophage T7 DNA primase

29 September 2017

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Mechanism and Stoichiometry of Interaction of DnaG Primase with DnaB Helicase of Escherichia coli in RNA Primer Synthesis

29 September 2017

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Affinity and sequence specificity of DNA binding and site selection for primer synthesis by Escherichia coli primase

29 September 2017

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29 September 2017

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29 September 2017

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A mutant Escherichia coli primase defective in elongation of primer RNA chains

29 September 2017

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Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins

29 September 2017

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Interaction of Escherichia coli primase with a phage G4ori(c)-E. coli SSB complex

29 September 2017

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The interaction between helicase and primase sets the replication fork clock

29 September 2017

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The extreme C terminus of primase is required for interaction with DnaB at the replication fork

29 September 2017

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Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork

29 September 2017

1 reference

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Requirement for a zinc motif for template recognition by the bacteriophage T7 primase

29 September 2017

1 reference

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Domains of Escherichia coli primase: functional activity of a 47-kDa N-terminal proteolytic fragment

29 September 2017

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Prokaryotic DNA replication

29 September 2017

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Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains

29 September 2017

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Role of conserved amino acids in the catalytic activity of Escherichia coli primase

29 September 2017

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Fluorometric assay for bacterial primases.

2 June 2018

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Evidence that discontinuous DNA replication in Escherichia coli is primed by approximately 10 to 12 residues of RNA starting with a purine

2 June 2018

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Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. II. Frequency of primer synthesis and efficiency of primer utilization control Okazaki fragment size

2 June 2018

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Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size

2 June 2018

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ppGpp inhibits the activity of Escherichia coli DnaG primase

2 June 2018

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Replication fork reactivation downstream of a blocked nascent leading strand

27 November 2018

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Crosstalk between primase subunits can act to regulate primer synthesis in trans.

27 November 2018

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Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.

27 November 2018

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Essential lysine residues in the RNA polymerase domain of the gene 4 primase-helicase of bacteriophage T7.

27 November 2018

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27 November 2018

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The role of zinc and the reactivity of cysteines in Escherichia coli primase

27 November 2018

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Magnesium acetate induces a conformational change in Escherichia coli primase.

27 November 2018

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Primer synthesis kinetics by Escherichia coli primase on single-stranded DNA templates.

27 November 2018

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Identification of the magnesium ion binding site in the catalytic center of Escherichia coli primase by iron cleavage

27 November 2018

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12 December 2020

DnaB helicase affects the initiation specificity of Escherichia coli primase on single-stranded DNA templates

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12 December 2020

Escherichia coli mutants with temperature-sensitive synthesis of DNA

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12 December 2020

Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis

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12 December 2020

A unified polymerase mechanism for nonhomologous DNA and RNA polymerases

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12 December 2020

The mechanism of action of T7 DNA polymerase

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12 December 2020

On the evaluation of the constants Vm and KM in enzyme reactions

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Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

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10.1016/J.STR.2012.05.017

Identifiers

DOI

2 references

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7 February 2020

1 reference

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7 February 2020

PubMed publication ID

22795082

2 references

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