Structural Basis for Iloprost as a Dual Peroxisome Proliferator-activated Receptor &#160;/&#160; Agonist (Q27670895)

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8 February 2020

title

Structural basis for iloprost as a dual peroxisome proliferator-activated receptor alpha/delta agonist (English)

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8 February 2020

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2

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8 February 2020

author name string

Lihua Jin

1

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8 February 2020

Hui Rong

3

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8 February 2020

Songyang Zheng

4

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8 February 2020

Shikan Jin

5

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8 February 2020

Rui Wang

6

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8 February 2020

Yong Li

7

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8 February 2020

language of work or name

English

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publication date

20 July 2011

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Journal of Biological Chemistry

8 February 2020

published in

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8 February 2020

volume

286

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8 February 2020

issue

36

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8 February 2020

page(s)

31473-31479

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Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents

8 February 2020

cites work

1 reference

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Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

20 March 2017

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Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

20 March 2017

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20 March 2017

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

20 March 2017

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

20 March 2017

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Going nuclear in metabolic and cardiovascular disease

7 April 2017

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Activation of nuclear receptors: a perspective from structural genomics

29 September 2017

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Inhaled iloprost for severe pulmonary hypertension

29 September 2017

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PPAR signaling in the control of cardiac energy metabolism

29 September 2017

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Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR).

29 September 2017

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cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla.

29 September 2017

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Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation

29 September 2017

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Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

29 September 2017

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Differential activation of adipogenesis by multiple PPAR isoforms.

2 June 2018

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Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

2 June 2018

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Has angiogenesis been invited to the PPARty?

2 June 2018

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Endothelial progenitor cells and angiogenesis join the PPARty

21 January 2018

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Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: a possible role for peroxisome proliferator-activated receptors.

21 January 2018

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Peroxisome proliferator-activated receptor alpha is crucial for iloprost-induced in vivo angiogenesis and vascular endothelial growth factor upregulation

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor

21 January 2018

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Long-Term Treatment of Primary Pulmonary Hypertension with Aerosolized Iloprost, a Prostacyclin Analogue

21 January 2018

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Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1

21 January 2018

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12 December 2020

Protection of endothelial survival by peroxisome proliferator-activated receptor-delta mediated 14-3-3 upregulation

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12 December 2020

Pharmacological profile of a novel carbacyclin derivative with high metabolic stability and oral activity in the rat

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12 December 2020

Identification and characterisation of a prostacyclin- like receptor in bovine coronary arteries using a specific and stable prostacyclin analogue, ciloprost, as radioactive ligand

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12 December 2020

Carbacyclin--a potent stable prostacyclin analogue for the inhibition of platelet aggregation

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.266023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775429%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775429%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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