Enterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin Assembly (Q27671688)

1

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Perttu Permi

7

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Maarit Hellman

2

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author name string

Brian Skehan

3

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John M Leong

Structural basis for regulation of the Crk signaling protein by a proline switch

5

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publication date

10 October 2012

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published in

Structure

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volume

20

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issue

10

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page(s)

1692-703

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cites work

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Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation

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Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix

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How viruses hijack cell regulation

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Cytoskeleton-modulating effectors of enteropathogenic and enterohaemorrhagic Escherichia coli: Tir, EspFU and actin pedestal assembly

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The mysterious unfoldome: structureless, underappreciated, yet vital part of any given proteome

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Protein dynamics and conformational disorder in molecular recognition

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IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation.

29 September 2017

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The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency

29 September 2017

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Local structural disorder imparts plasticity on linear motifs.

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Characterization of TccP-mediated N-WASP activation during enterohaemorrhagic Escherichia coli infection

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TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton

29 September 2017

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Interactions with aromatic rings in chemical and biological recognition

29 September 2017

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Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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27 November 2018

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27 November 2018

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27 November 2018

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Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir.

27 November 2018

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EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly

27 November 2018

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Preformed structural elements feature in partner recognition by intrinsically unstructured proteins.

27 November 2018

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27 November 2018

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Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins

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Sequence correction of random coil chemical shifts: correlation between neighbor correction factors and changes in the Ramachandran distribution

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