Structure of the agonist-bound neurotensin receptor (Q27674395)

2

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Brian Kloss

5

object named as

Brian Kloss

0 references

Christopher G. Tate

object named as

Christopher G Tate

10

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author name string

Jim F White

1

0 references

Yoko Shibata

3

0 references

James Love

4

0 references

Brian Kloss

5

0 references

Feng Xu

6

0 references

Jelena Gvozdenovic-Jeremic

7

0 references

Priyanka Shah

8

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Joseph Shiloach

9

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Reinhard Grisshammer

Structure of the δ-opioid receptor bound to naltrindole

11

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language of work or name

English

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publication date

25 October 2012

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published in

Nature

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volume

490

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issue

7421

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page(s)

508-13

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cites work

1 reference

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Structure of the human κ-opioid receptor in complex with JDTic

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Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

20 March 2017

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Diversity and modularity of G protein-coupled receptor structures

20 March 2017

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

20 March 2017

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

20 March 2017

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Crystal structure of metarhodopsin II

20 March 2017

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The structural basis of agonist-induced activation in constitutively active rhodopsin

20 March 2017

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

20 March 2017

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

20 March 2017

1 reference

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

20 March 2017

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Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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Crystal structure of opsin in its G-protein-interacting conformation

20 March 2017

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

20 March 2017

1 reference

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Structural changes in a cryo-cooled protein crystal owing to radiation damage

20 March 2017

1 reference

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Specific chemical and structural damage to proteins produced by synchrotron radiation

20 March 2017

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Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor

20 March 2017

1 reference

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Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor

20 March 2017

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Features and development of Coot

20 March 2017

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Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?

20 March 2017

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

20 March 2017

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Increased plasma neurotensin concentrations in patients with Parkinson's disease

20 March 2017

1 reference

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Molecular cloning of a levocabastine-sensitive neurotensin binding site

20 March 2017

1 reference

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The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

20 March 2017

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Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid

20 March 2017

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Constitutive activation of the neurotensin receptor 1 by mutation of Phe(358) in Helix seven

20 March 2017

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

20 March 2017

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Crystallizing membrane proteins using lipidic mesophases

7 April 2017

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A crystal clear solution for determining G-protein-coupled receptor structures

7 April 2017

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Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?

29 September 2017

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Agonist-bound structures of G protein-coupled receptors

29 September 2017

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Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals.

29 September 2017

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Structural insights into agonist-induced activation of G-protein-coupled receptors

29 September 2017

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Highly conserved tyrosine stabilizes the active state of rhodopsin

29 September 2017

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Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

29 September 2017

1 reference

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Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.

29 September 2017

1 reference

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Thermostabilization of the neurotensin receptor NTS1.

29 September 2017

1 reference

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Involvement of neurotensin in cancer growth: evidence, mechanisms and development of diagnostic tools

29 September 2017

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Structure of bovine rhodopsin in a trigonal crystal form.

29 September 2017

1 reference

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The conformation of neurotensin bound to its G protein-coupled receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482300

Targeting neurotensin receptors with agonists and antagonists for therapeutic purposes

29 September 2017

1 reference

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The bombesin receptor subtypes have distinct G protein specificities

29 September 2017

1 reference

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Selective reconstitution of gastrin-releasing peptide receptor with G alpha q

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482300

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482300

Lipidic cubic phases: a novel concept for the crystallization of membrane proteins

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482300

Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists

29 September 2017

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Proposed ligand binding site of the transmembrane receptor for neurotensin(8-13).

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482300

Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin

29 September 2017

1 reference

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Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

29 September 2017

1 reference

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Structure and functional expression of the cloned rat neurotensin receptor

2 June 2018

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Novel insights into GPCR-peptide interactions: mutations in extracellular loop 1, ligand backbone methylations and molecular modeling of neurotensin receptor 1.

2 June 2018

1 reference

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Functional role of the "ionic lock"--an interhelical hydrogen-bond network in family A heptahelical receptors.

21 January 2018

1 reference

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Efficient expression of the gene for spinach phosphoribulokinase in Pichia pastoris and utilization of the recombinant enzyme to explore the role of regulatory cysteinyl residues by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11558

Absorbed dose calculations for macromolecular crystals: improvements to RADDOSE.

21 January 2018

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Translational research: A UK tissue bank for breast tumours

21 January 2018

1 reference

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Identification of residues involved in neurotensin binding and modeling of the agonist binding site in neurotensin receptor 1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23051748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11558

1 reference

Dimensions Publication ID

761641

1008803082

0 references

761641

1 reference

1 reference

1 reference