Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine (Q27674991)

1

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Yeyun Zhou

2

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Saba Khan

3

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Kirk W Deitsch

4

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Quan Hao

5

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Hening Lin

Structure of Sir2Tm bound to a propionylated peptide

6

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language of work or name

1 reference

20 January 2012

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published in

ACS Chemical Biology

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volume

7

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issue

1

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page(s)

155-9

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cites work

1 reference

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Structure and autoregulation of the yeast Hst2 homolog of Sir2

20 March 2017

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Structure of a Sir2 enzyme bound to an acetylated p53 peptide

20 March 2017

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Structure of the histone deacetylase SIRT2

20 March 2017

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Crystal structure of a SIR2 homolog-NAD complex

20 March 2017

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The CCP4 suite: programs for protein crystallography

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

20 March 2017

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

20 March 2017

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Mammalian sirtuins: biological insights and disease relevance

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Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

7 April 2017

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Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites

24 May 2017

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Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

24 May 2017

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Identification and characterization of propionylation at histone H3 lysine 23 in mammalian cells

29 September 2017

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N-lysine propionylation controls the activity of propionyl-CoA synthetase

29 September 2017

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Lysine propionylation and butyrylation are novel post-translational modifications in histones

29 September 2017

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The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece

29 September 2017

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Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase

29 September 2017

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Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues

2 June 2018

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Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

2 June 2018

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Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases

27 November 2018

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Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity

27 November 2018

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Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD+ and Acetylated Peptide

27 November 2018

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Acetylation-dependent ADP-ribosylation by Trypanosoma brucei Sir2

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21992006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21992006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB200230X

1 reference

4182088

4182088

1 reference

1 reference

1 reference