Antibacterial drug leads targeting isoprenoid biosynthesis (Q27675524)

2

Yonghui

Zhang

1 reference

19 October 2023

William Sinko

3

William

Sinko

1 reference

19 October 2023

Mary E Hensler

4

Mary E

Hensler

1 reference

19 October 2023

Joshua Olson

5

Joshua

Olson

1 reference

19 October 2023

Katie J Molohon

6

Katie J

Molohon

1 reference

19 October 2023

Steffen Lindert

7

Steffen

Lindert

1 reference

19 October 2023

Kai Li

9

Kai

Li

1 reference

19 October 2023

Ke Wang

10

Ke

Wang

1 reference

19 October 2023

Yang Wang

11

Yang

Wang

1 reference

19 October 2023

Yi-Liang Liu

12

Yi-Liang

Liu

1 reference

19 October 2023

Anna Sankovsky

13

Anna

Sankovsky

1 reference

19 October 2023

César Augusto F de Oliveira

14

César Augusto F

Proceedings of the National Academy of Sciences of the United States of America

de Oliveira

1 reference

19 October 2023

language of work or name

English

0 references

publication date

2 January 2013

0 references

published in

0 references

volume

110

0 references

page(s)

123-8

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issue

1

0 references

cites work

HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Structure-Based Inhibitors Exhibit Differential Activities againstHelicobacter pyloriandEscherichia coliUndecaprenyl Pyrophosphate Synthases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Inhibitors targeting on cell wall biosynthesis pathway of MRSA.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Terpene biosynthesis: modularity rules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Targeting isoprenoid biosynthesis for drug discovery: bench to bedside

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activities against antibiotic-resistant strains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Optimization of high throughput virtual screening by combining shape-matching and docking methods

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Lipid intermediates in the biosynthesis of bacterial peptidoglycan

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Discovery and initial development of a novel class of antibacterials: inhibitors of Staphylococcus aureus transcription/translation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Scoring residue conservation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Influence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244

Synthesis and biological activity of isopentenyl diphosphate analogues

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Kinetic studies of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase reaction using 3-desmethyl allylic substrate analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Different reaction mechanisms for cis- and trans-prenyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Mechanism of cis-prenyltransferase reaction probed by substrate analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Resistance mapping and mode of action of a novel class of antibacterial anthranilic acids: evidence for disruption of cell wall biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

EUCAST Definitive Document E.Def 1.2, May 2000: Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Bio3d: an R package for the comparative analysis of protein structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1219899110

Synergistic and additive killing by antimicrobial factors found in human airway surface liquid

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538244