The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels (Q27676741)

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25 February 2020

title

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels (English)

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25 February 2020

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3

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25 February 2020

Frank Bosmans

4

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25 February 2020

Frank Bosmans

5

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25 February 2020

Graham M Nicholson

6

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25 February 2020

Mehdi Mobli

7

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25 February 2020

Glenn F King

8

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25 February 2020

1

Niraj S Bende

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25 February 2020

author name string

Eunji Kang

2

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language of work or name

English

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publication date

6 March 2013

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25 February 2020

published in

Biochemical Pharmacology

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25 February 2020

volume

85

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25 February 2020

issue

10

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25 February 2020

page(s)

1542-1554

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A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a

25 February 2020

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A novel family of insect-selective peptide neurotoxins targeting insect large-conductance calcium-activated K+ channels isolated from the venom of the theraphosid spider Eucratoscelus constrictus.

29 September 2017

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29 September 2017

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29 September 2017

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μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

29 September 2017

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A scorpion venom neurotoxin paralytic to insects that affects sodium current inactivation: purification, primary structure, and mode of action

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27 November 2018

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The omega-atracotoxins: selective blockers of insect M-LVA and HVA calcium channels

27 November 2018

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27 November 2018

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CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons.

27 November 2018

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Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Nav1.5 and Kv2.1 channels.

27 November 2018

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The cross channel activities of spider neurotoxin huwentoxin-I on rat dorsal root ganglion neurons.

27 November 2018

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Isolation and characterization of Jingzhaotoxin-V, a novel neurotoxin from the venom of the spider Chilobrachys jingzhao.

27 November 2018

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An improved strategy for high-level production of TEV protease in Escherichia coli and its purification and characterization

27 November 2018

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Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels

27 November 2018

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SNX482 selectively blocks P/Q Ca2+ channels and delays the inactivation of Na+ channels of chromaffin cells

27 November 2018

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Delta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels.

27 November 2018

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omega-Toxins affect Na+ currents in neurosecretory insect neurons.

27 November 2018

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delta-Atracotoxins from australian funnel-web spiders compete with scorpion alpha-toxin binding but differentially modulate alkaloid toxin activation of voltage-gated sodium channels.

27 November 2018

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mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes.

27 November 2018

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Ca2+ currents in central insect neurons: electrophysiological and pharmacological properties.

27 November 2018

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Separation and identification of multiple potassium currents regulating the pacemaker activity of insect neurosecretory cells (DUM neurons).

27 November 2018

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Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function

27 November 2018

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10.1016/J.BCP.2013.02.030

27 November 2018

Identifiers

DOI

2 references

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25 February 2020

1 reference

2 references

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25 February 2020

PubMed publication ID

23473802

2 references