Structural Basis for Molecular Recognition at Serotonin Receptors (Q27676926)

5

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Vadim Cherezov

21

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Karsten Melcher

14

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Huixian Wu

Huixian Wu

4

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Fang Bai

Fang Bai

16

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Raymond C. Stevens

Raymond C Stevens

22

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Jiang Hualiang

19

Hualiang Jiang

0 references

John D McCorvy

11

John D McCorvy

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Bryan L. Roth

20

Bryan L Roth

0 references

Gye Won Han

7

Gye Won Han

0 references

Eyal Vardy

10

Eyal Vardy

0 references

Chenghai Zhang

15

Chenghai Zhang

0 references

Wei Liu

8

Wei Liu

0 references

author name string

Chong Wang

1

0 references

Yi Jiang

2

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Jinming Ma

3

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Xi-Ping Huang

9

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Xiang Gao

12

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X Edward Zhou

13

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Huaiyu Yang

17

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Linlin Yang

18

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H Eric Xu

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

23

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language of work or name

English

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publication date

3 May 2013

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published in

Science

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volume

340

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issue

6132

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page(s)

610-4

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cites work

1 reference

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Diversity and modularity of G protein-coupled receptor structures

20 March 2017

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Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

20 March 2017

1 reference

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Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor

20 March 2017

1 reference

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

20 March 2017

1 reference

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Drugs and valvular heart disease

20 March 2017

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Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

20 March 2017

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Valvular heart disease associated with fenfluramine-phentermine

20 March 2017

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International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

20 March 2017

1 reference

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Structural Features for Functional Selectivity at Serotonin Receptors

20 March 2017

1 reference

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Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

22 April 2017

1 reference

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

22 April 2017

1 reference

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Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

22 April 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

22 April 2017

1 reference

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Features and development of Coot

22 April 2017

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Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

22 April 2017

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The genetic design of signaling cascades to record receptor activation

22 April 2017

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Structure of the human κ-opioid receptor in complex with JDTic

22 April 2017

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Automated design of ligands to polypharmacological profiles.

22 April 2017

1 reference

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The expanded biology of serotonin

29 September 2017

1 reference

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Current and prospective pharmacological targets in relation to antimigraine action

29 September 2017

1 reference

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Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

Molecular biology of serotonin receptors structure and function at the molecular level

29 September 2017

1 reference

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Serotonin releasing agents. Neurochemical, therapeutic and adverse effects

29 September 2017

1 reference

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Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

A single point mutation increases the affinity of serotonin 5-HT1D alpha, 5-HT1D beta, 5-HT1E and 5-HT1F receptors for beta-adrenergic antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

Migraine: pathophysiology, pharmacology, treatment and future trends.

2 June 2018

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Anorexogen-related cardiac valvulopathy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644373

Pharmaceutical approval update

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Assessment of the roles of serines 5.43(239) and 5.46(242) for binding and potency of agonist ligands at the human serotonin 5-HT2A receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phasercrystallographic software

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0021889807021206

Epik: a software program for pK( a ) prediction and protonation state generation for drug-like molecules

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1007/S10822-007-9133-Z

Identifiers

DOI

10.1126/SCIENCE.1232807

1 reference

ADS bibcode

2013Sci...340..610W

0 references

1 reference

1 reference

PubMed publication ID

23519210

1 reference