Atomic View of a Toxic Amyloid Small Oligomer (Q27677948)

1

0 references

Duilio Cascio

11

0 references

Meytal Landau

9

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David Eisenberg

13

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Minglei Zhao

6

Minglei Zhao

0 references

Jiyong Park

Jiyong Park

5

0 references

Julian P Whitelegge

4

Julian P Whitelegge

0 references

Charles G. Glabe

12

Charles Glabe

0 references

Anna Pensalfini

7

Anna Pensalfini

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author name string

Cong Liu

2

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Michael R Sawaya

3

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Angela B Soriaga

8

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Poh K Teng

Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics

10

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language of work or name

English

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publication date

9 March 2012

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published in

Science

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volume

335

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issue

6073

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page(s)

1228-31

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cites work

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Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

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Refinement of macromolecular structures by the maximum-likelihood method

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Shape complementarity at protein/protein interfaces

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

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Alpha-crystallin can function as a molecular chaperone

7 April 2017

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Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity

7 April 2017

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β-Barrel topology of Alzheimer's β-amyloid ion channels

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29 September 2017

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Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

29 September 2017

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αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide

29 September 2017

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29 September 2017

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Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils

29 September 2017

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Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures

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Amyloid formation by globular proteins under native conditions

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Crystallin proteins and amyloid fibrils

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29 September 2017

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29 September 2017

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

29 September 2017

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Polymorphism in the intermediates and products of amyloid assembly

29 September 2017

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Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies

29 September 2017

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29 September 2017

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29 September 2017

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Fibril fragmentation enhances amyloid cytotoxicity

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The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition

2 June 2018

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Pore-forming proteins share structural and functional homology with amyloid oligomers

27 November 2018

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27 November 2018

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27 November 2018

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inferred from PubMed ID database lookup

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Conformational and geometrical properties of beta-sheets in proteins. I. Parallel beta-sheets

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PubMed

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Phasercrystallographic software

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Identifiers

DOI

10.1126/SCIENCE.1213151

1 reference

1437641

1437641

1 reference

1 reference

1 reference