Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds (Q27678492)

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English	Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds	scientific article

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scholarly article

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Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds (English)

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Schistosoma japonicum

object named as

Schistosoma japonicum

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based on heuristic

inferred from title

object named as

Shuqi Wang

5

1 reference

ORCID Public Data File 2021

author name string

Jian Liu

1

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David H Dyer

2

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Jingdong Cheng

3

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Jipeng Wang

4

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Zhong Yang

6

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Xiaoning Wang

7

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Wei Hu

8

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publication date

5 June 2013

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Parasites and Vectors

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6

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1

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162

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Structure of aldose reductase from Giardia lamblia

1 reference

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20 March 2017

Structural and functional characterization ofSchistosoma mansoniThioredoxin

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20 March 2017

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

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20 March 2017

Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10

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20 March 2017

Likelihood-enhanced fast translation functions

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20 March 2017

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20 March 2017

PHENIX: building new software for automated crystallographic structure determination

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20 March 2017

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

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20 March 2017

Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

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20 March 2017

Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni

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20 March 2017

Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni

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20 March 2017

Aldose reductase induction: a novel response to oxidative stress of smooth muscle cells

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20 March 2017

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7 April 2017

Molecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from Schistosoma japonicum

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29 September 2017

Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula

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29 September 2017

Mitoxantrone as a prospective photosensitizer for photodynamic therapy of breast cancer.

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29 September 2017

Low-molecular-mass antioxidants in parasites.

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29 September 2017

Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma

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29 September 2017

Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders.

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29 September 2017

Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening.

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29 September 2017

Understanding the role of aldose reductase in ocular inflammation

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29 September 2017

Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle.

1 reference

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29 September 2017

Failure of standard treatment with praziquantel in two returned travelers with Schistosoma haematobium infection

1 reference

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29 September 2017

Use of praziquantel for clinical treatment and morbidity control of schistosomiasis japonica in China: a review of 30 years' experience

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29 September 2017

The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase

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29 September 2017

Potentiation of the antimalarial agent rufigallol.

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29 September 2017

Crystallization of ribozymes and small RNA motifs by a sparse matrix approach

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29 September 2017

A glutathione-specific aldose reductase of Leishmania donovani and its potential implications for methylglyoxal detoxification pathway.

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2 June 2018

In vitro inhibition of lens aldose reductase by (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-yl)-acetic acid in enzyme preparations isolated from diabetic rats

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2 June 2018

Pathogenesis of diabetic neuropathy--do hyperglycemia and aldose reductase inhibitors affect neuroactive steroid formation in the rat sciatic nerves?

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2 June 2018

Schistosomiasis control: experiences and lessons from China.

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21 January 2018

Is there reduced susceptibility to praziquantel in Schistosoma japonicum? Evidence from China

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21 January 2018

Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets

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21 January 2018

Aldose reductase in keratinocytes attenuates cellular apoptosis and senescence induced by UV radiation.

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21 January 2018

The in vitro effect of mefloquine and praziquantel against juvenile and adult Schistosoma japonicum

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21 January 2018

Effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy in patients with type 2 diabetes, in relation to suppression of N(ɛ)-carboxymethyl lysine

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21 January 2018

Analysis of rhubarb anthraquinones and bianthrones by microemulsion electrokinetic chromatography

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21 January 2018

Microcalorimetric assay on the antimicrobial property of five hydroxyanthraquinone derivatives in rhubarb (Rheum palmatum L.) to Bifidobacterium adolescentis

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27 November 2018

The anti-schistosomal drug praziquantel is an adenosine antagonist

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27 November 2018

Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase

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27 November 2018

Selectivity determinants of inhibitor binding to the tumour marker human aldose reductase-like protein (AKR1B10) discovered from molecular docking and database screening

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12 December 2020

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Hysteresis in thioredoxin-glutathione reductase (TGR) from the adult stage of the liver fluke Fasciola hepatica

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/23734964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1756-3305-6-162

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Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1756-3305-6-162

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